Artisan Aphakia Lens for the Correction of Aphakia in Children

NCT ID: NCT01547442

Last Updated: 2024-08-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

SUSPENDED

Clinical Phase

NA

Total Enrollment

300 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-01-31

Study Completion Date

2025-12-31

Brief Summary

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The purpose of this study is to determine the safety and effectiveness of the Artisan Aphakia Lens in the treatment of aphakia in children.

Detailed Description

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Conditions

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Aphakia

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Artisan Aphakia Intraocular Lens

Implantation of an Artisan intraocular lens to correct aphakia in children

Group Type EXPERIMENTAL

Artisan Aphakia Intraocular Lens

Intervention Type DEVICE

Implantation of an intraocular lens

Interventions

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Artisan Aphakia Intraocular Lens

Implantation of an intraocular lens

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* 2 to 21 years of age
* Have a visually significant cataract or need IOL replacement surgery
* Compromised capsular bag prohibiting implantation of standard posterior IOL
* Subject or parent/guardian must be able to comply with visit schedule and study requirements
* Subject's legal representative must be able to sign the Informed Consent

Exclusion Criteria

* Under 2 years of age
* Unable to meet Postoperative evaluation requirements
* No useful vision or vision potential in fellow eye
* Mentally retarded patients
* History of corneal disease
* Abnormality of the iris or ocular structure
* ACD less than 3.2 mm
* Uncontrolled glaucoma
* IOP \> 25 mmHg
* Chronic or recurrent uveitis
* Preexisting macular pathology that may complicate the ability to assess the benefit of this lens
* Retinal detachment or family history
* Retinal disease that may limit visual potential
* Optic nerve disease that may limit visual potential
* Diabetes mellitus
* Pregnant, lactating or plan to become pregnant
Minimum Eligible Age

2 Years

Maximum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Ophtec USA

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Abraham Farhan

Role: STUDY_DIRECTOR

Sponsor GmbH

Locations

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Phoenix Children's Hospital

Phoenix, Arizona, United States

Site Status

The Vision Center

Los Angeles, California, United States

Site Status

Indiana University, Riley Hospital for Children

Indianapolis, Indiana, United States

Site Status

Harvard University, Boston Children's Hospital

Boston, Massachusetts, United States

Site Status

University of Minnesota, MN Lions Children's Eye Clinic

Minneapolis, Minnesota, United States

Site Status

Mayo Clinic

Rochester, Minnesota, United States

Site Status

Children's Mercy Hospital and Clinics

Kansas City, Missouri, United States

Site Status

Washington University, St. Louis Children's Hospital

St Louis, Missouri, United States

Site Status

Rosenthal Eye and Facial Plastic Surgery

Great Neck, New York, United States

Site Status

New York Medical College, Westchester Medical Center

Valhalla, New York, United States

Site Status

Nationwide Children's Hospital, Pediatric Ophthalmology Associates

Columbus, Ohio, United States

Site Status

University Hospitals Case Medical Center, Rainbow Babies and Children's Hospital

Mayfield Heights, Ohio, United States

Site Status

Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, United States

Site Status

University of Pittsburgh Medical Center, Children's Hospital of Pittsburgh

Pittsburgh, Pennsylvania, United States

Site Status

Medical University of South Carolina, Storm Eye Institute

Charleston, South Carolina, United States

Site Status

University of Texas, Southwestern Medical Center

Dallas, Texas, United States

Site Status

University of Texas, Robert Cizik Eye Clinic

Houston, Texas, United States

Site Status

Moran Eye Center

Salt Lake City, Utah, United States

Site Status

Credit Valley Eyecare

Mississauga, Ontario, Canada

Site Status

Countries

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United States Canada

Other Identifiers

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Artisan Pediatric Aphakia

Identifier Type: -

Identifier Source: org_study_id

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