Effect of Prostacyclin on Haemostasis in Abdominal Surgery
NCT ID: NCT01528943
Last Updated: 2021-03-10
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE1
40 participants
INTERVENTIONAL
2012-03-31
2014-01-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
BASIC_SCIENCE
NONE
Study Groups
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Prostacyclin
Treatment with prostacyclin
Prostacycline
Continuous infusion peri -and 6 hours postoperatively of prostacycline 1 ng/kg/min
Isotonic saline
Treatment with isotonic saline
Isotonic saline
same volume as the group that are allocated to prostacycline
Interventions
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Prostacycline
Continuous infusion peri -and 6 hours postoperatively of prostacycline 1 ng/kg/min
Isotonic saline
same volume as the group that are allocated to prostacycline
Eligibility Criteria
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Inclusion Criteria
* Undergoing Whipple surgery or liver resection
* Able and willing to give informed consent
Exclusion Criteria
2. In treatment with platelet ADP receptor inhibitors or heparin (not including thrombosis prophylaxis), Factor Xa inhibitors, trombininhibitors, Vitamin K antagonists
3. Autoimmune disease
4. Intracranial bleeding within the last 6 months
5. Acute coronary syndrome or myocardial infarction within the last 6 months
6. Congestive heart disease
7. Pregnant or breastfeeding
8. Participating in another clinical study within the last 30 days
9. Liver cirrhosis
10. Need for renal replacement therapy
18 Years
ALL
No
Sponsors
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Rigshospitalet, Denmark
OTHER
Responsible Party
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Pär Johansson
Medical Director
Principal Investigators
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Pär Johansson I Johansson, MD DMSc MPA
Role: PRINCIPAL_INVESTIGATOR
Professor
Locations
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Rigshospitalet
Copenhagen, Region Sjælland, Denmark
Countries
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Other Identifiers
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ET Abdominal
Identifier Type: -
Identifier Source: org_study_id
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