Effect of Timolol on Refractive Outcomes in Eyes With Myopic Regression After LASIK: a Randomized Clinical Trial

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

45 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-03-31

Study Completion Date

2010-12-31

Brief Summary

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In this randomized controlled clinical trial, we compare the effects of timolol versus placebo for treatment of myopic regression after LASIK

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Detailed Description

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Conditions

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Myopic Regression

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Control group

included patients who received artificial tear twice a day as control group.

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DRUG

artificial tear twice a day

Timolol group

included the patients with myopic regression who received timolol 0.5% eye drop twice a day

Group Type EXPERIMENTAL

Timolol

Intervention Type DRUG

Interventions

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Timolol

Intervention Type DRUG

Placebo

artificial tear twice a day

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients with myopic regression equal or more than 0.5 D with minimum age of 20 years,
* cylinder ≤ -1.00 D,
* corrected distance visual acuity (CDVA) of at least 20/40 were included.

Exclusion Criteria

* Patients with a history of previous ocular surgery,
* keratoconus or any ectatic corneal disorder,
* keratoconus suspect by topography,
* preoperative corneal opacity,
* any corneal dystrophies,
* presence of pterygium,
* retinal disorders,
* collagen vascular disorders,
* diabetes mellitus,
* glaucoma,
* cataract,
* pregnancy,
* breast feeding
* systemic corticosteroid therapy were excluded.

Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No