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Proprioceptive Postural Control and Chronic Obstructive Pulmonary Disease (COPD)

NCT ID: NCT01505543

Last Updated: 2013-12-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-01-31

Study Completion Date

2012-09-30

Brief Summary

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Proprioceptive weighting changes may explain differences in postural control performance. In addition, the respiratory movement has a disturbing effect on postural balance. Postural balance seems to be impaired in individuals with respiratory disorders. Increased risk of falling is reported in individuals with chronic obstructive pulmonary disease. Besides the essential role of respiration, the diaphragm may also play an important role in the control of the trunk and postural balance.

The aim of the study is to clarify whether proprioceptive postural control is impaired in individuals with chronic obstructive pulmonary disease.

Detailed Description

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Conditions

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Proprioceptive Postural Control Chronic Obstructive Pulmonary Disease

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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chronic obstructive pulmonary disease

No interventions assigned to this group

healthy matched controls

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Age: 40-80 years old
* Spirometry (post-bronchodilator) based diagnosis of COPD (GOLD criteria)
* Willingness to sign the informed consent


* Age: 40-80 years old
* No COPD (spirometry based: FEV1/FVC ≥ 0.7 and FEV1 \> 80%)
* Willingness to sign the informed consent

Exclusion Criteria

* History of major trauma and/or major orthopedic surgery of the spine, the pelvis or the lower quadrant
* One of the following conditions: Parkinson, multiple sclerosis, stroke, history of vestibular disorder
* Respiratory disorder other than COPD
* α1-antitrypsin deficiency
* Known history of significant inflammatory disease other than COPD
* COPD exacerbation within 4 weeks prior to study
* Lung surgery
* Recent diagnosis of cancer
* Therapy with oral corticosteroids in the last 6 weeks
* Significant cardiovascular comorbidity
Minimum Eligible Age

40 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Universitaire Ziekenhuizen KU Leuven

OTHER

Sponsor Role collaborator

KU Leuven

OTHER

Sponsor Role lead

Responsible Party

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Simon Brumagne

Prof. dr. Simon Brumagne

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Simon Brumagne, PhD

Role: PRINCIPAL_INVESTIGATOR

KU Leuven

Thierry Troosters, PhD

Role: PRINCIPAL_INVESTIGATOR

KU Leuven

Wim Janssens, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

KU Leuven

Marc Decramer, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

KU Leuven

Locations

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Katholieke Universiteit Leuven

Leuven, Vlaams-Brabant, Belgium

Site Status

Countries

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Belgium

References

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Janssens L, Brumagne S, Polspoel K, Troosters T, McConnell A. The effect of inspiratory muscles fatigue on postural control in people with and without recurrent low back pain. Spine (Phila Pa 1976). 2010 May 1;35(10):1088-94. doi: 10.1097/BRS.0b013e3181bee5c3.

Reference Type BACKGROUND
PMID: 20393397 (View on PubMed)

Other Identifiers

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1.5.104.03, G.0674.09

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

2012_SBrumagne_COPD

Identifier Type: -

Identifier Source: org_study_id