A Continuous, Non-Invasive, Real-time Method for Estimating and Predicting Intracranial Hypertension
NCT ID: NCT01448681
Last Updated: 2019-09-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
32 participants
OBSERVATIONAL
2011-08-31
2019-07-31
Brief Summary
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1. Develop models to estimate ICP and cerebral perfusion pressure (CPP) after traumatic brain injury in humans.
2. Predict and anticipate changes in ICP for preemptive management purposes.
3. Analyze characteristics of changes in ICP after treatment failure.
4. Analyze data to predict/anticipate confounding physiologic factors that affect ICP and its treatment.
5. Test the resulting models in real time.
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Detailed Description
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Conditions
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Study Design
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CASE_ONLY
PROSPECTIVE
Study Groups
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SICU patients with ICP
Surgical intensive care unit patients with elevated intracranial pressure
No Interventions
Interventions
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No Interventions
Eligibility Criteria
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Inclusion Criteria
* age 18-89 years
* health care provider indicating the need for hyperosmolar therapy for elevated ICP
Exclusion Criteria
* incarceration
* brain death (GCS 3 with fixed, dilated pupils)
* life-threatening systemic injuries (Abbreviated Injury Scale (AIS) \>4 in an organ system other than CNS)
18 Years
89 Years
ALL
No
Sponsors
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University of Colorado, Denver
OTHER
Responsible Party
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Principal Investigators
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Steven Moulton, MD
Role: PRINCIPAL_INVESTIGATOR
University of Colorado, Denver
Locations
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Denver Health Medical Center
Denver, Colorado, United States
Countries
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Other Identifiers
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10-1412
Identifier Type: -
Identifier Source: org_study_id
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