Correlation Intraocular Pressure With Intracranial Pressure

NCT ID: NCT03344432

Last Updated: 2017-11-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-06-10

Study Completion Date

2019-12-31

Brief Summary

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Severe Trauma Brain Injury (TBIs) is a public health problem and monitoring of Intracranial Pressure (ICP) is a determinant key of it prognosis. Within the noninvasive methods to estimate the ICP, the measurement of intraocular pressure has been proposed because of its biological plausibility (proximity of the eye to the encephalic contend).

Objective. Correlate intraocular pressure with ICP in children with TBIs and obtain their utility values.

Detailed Description

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Severe Trauma Brain Injury (TBIs) is a public health problem and monitoring of Intracranial Pressure (ICP) is a determinant key of it prognosis. Within the noninvasive methods to estimate the ICP, the measurement of intraocular pressure has been proposed because of its biological plausibility (proximity of the eye to the encephalic contend).

Objective. Correlate intraocular pressure with ICP in children with TBIs and obtain their utility values.

Material and methods. Correlation and diagnostic test design study. Inclusion criteria: children with TBIs admitted to the emergency room and indication of catheter for ICP measurement.

Exclusion criteria: injury or ophthalmic disease, glaucoma, encephalic death. Intraocular pressure was measured with electronic tonometer in both eyes prior to placement of the catheter for ICP measurement.

Correlation was estimated with Spearman's Rho. The utility values of the diagnostic test were obtained from an Receiver Operating Characteristic curve.

Conditions

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Intraocular Pressure Intracranial Pressure Increase Trauma, Brain Children, Only

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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With intraocular pressure high

Intracranial pressure equal or more than 20 mmHg

with intraocular pressure high

Intervention Type DIAGNOSTIC_TEST

Measurement of intraocular pressure The measurement will be made with a electronic minimum contact tonometer for measuring intraocular pressure immediately before the placement of the invasive catheter for measurement of intracranial pressure.

without intraocular pressure high

Intervention Type DIAGNOSTIC_TEST

Measurement of intraocular pressure The measurement will be made with a electronic minimum contact tonometer for measuring intraocular pressure immediately before the placement of the invasive catheter for measurement of intracranial pressure.

Without intraocular pressure high

Intracranial pressure smaller than 20 mmHg

with intraocular pressure high

Intervention Type DIAGNOSTIC_TEST

Measurement of intraocular pressure The measurement will be made with a electronic minimum contact tonometer for measuring intraocular pressure immediately before the placement of the invasive catheter for measurement of intracranial pressure.

without intraocular pressure high

Intervention Type DIAGNOSTIC_TEST

Measurement of intraocular pressure The measurement will be made with a electronic minimum contact tonometer for measuring intraocular pressure immediately before the placement of the invasive catheter for measurement of intracranial pressure.

Interventions

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with intraocular pressure high

Measurement of intraocular pressure The measurement will be made with a electronic minimum contact tonometer for measuring intraocular pressure immediately before the placement of the invasive catheter for measurement of intracranial pressure.

Intervention Type DIAGNOSTIC_TEST

without intraocular pressure high

Measurement of intraocular pressure The measurement will be made with a electronic minimum contact tonometer for measuring intraocular pressure immediately before the placement of the invasive catheter for measurement of intracranial pressure.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

1. Children with severe trauma brain injury (Coma Glasgow Scale smaller than 9 points),
2. who have been admitted to the pediatric emergency room
3. and in whom the treating neurosurgeon has decided to place a catheter for intracranial pressure measurement.

Exclusion Criteria

1. Ocular trauma,
2. brain death,
3. know eye disease,
4. refusal of parents or guardians to participate in the study.
Minimum Eligible Age

2 Years

Maximum Eligible Age

15 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hospital Civil de Guadalajara

OTHER

Sponsor Role lead

Responsible Party

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KARLA ISIS AVILES MARTINEZ

Dra. Karla Isis Avilés-Martínez

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Karla Isis I Aviles Martinez, PhD

Role: PRINCIPAL_INVESTIGATOR

Hospital Civil Fray Antonio Alcalde

Locations

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Hospital Civil Fray Antonio Alcalde

Guadalajara, Jalisco, Mexico

Site Status RECRUITING

Countries

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Mexico

Central Contacts

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Karla Isis I Aviles-Martinez, PhD

Role: CONTACT

Phone: 39424400

Email: [email protected]

Adriana López-Enríquez, MD

Role: CONTACT

Phone: 39424400

Email: [email protected]

Facility Contacts

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Karla Isis Aviles-Martinez, PhD

Role: primary

Juan Luis Soto-Mancilla, Master

Role: backup

Other Identifiers

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HCG/CI-0693/15

Identifier Type: -

Identifier Source: org_study_id