Special Investigation (All Cases) of LipaCreon in Patients With Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis

NCT ID: NCT01427712

Last Updated: 2022-06-10

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

View full results

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

24 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-08-31

Study Completion Date

2018-03-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study aims at collecting the information related to the safety and effectiveness in the pancreatic exocrine insufficiency patients due to cystic fibrosis receiving the treatment with LipaCreon in order to evaluate the effective and safe use of LipaCreon.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Cystic Fibrosis Exocrine Pancreatic Insufficiency Pancreatic Diseases Digestive System Diseases

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

LipaCreon

In general, pancrelipase 600 mg/dose was orally administered immediately after a meal, 3 times a day.

Also, the dose was adjusted appropriately according to the patient's condition.

Pancrelipase

Intervention Type DRUG

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Pancrelipase

Intervention Type DRUG

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

Lipacreon

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patients who receive LipaCreon for the replacement of pancreatic digestive enzymes in pancreatic exocrine insufficiency due to cystic fibrosis

Exclusion Criteria

* Patients with a history of hypersensitivity to the ingredient of LipaCreon.
* Patients with a history of hypersensitivity to porcine protein
Minimum Eligible Age

1 Year

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Mylan Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Shigenori Haruna

Role: STUDY_DIRECTOR

Mylan EPD G.K.

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Site Reference ID/Investigator# 73813

Aichi, , Japan

Site Status

Site reference ID/Investigator # 96698

Aichi, , Japan

Site Status

Research facility ID ORG-000141

Aichi, , Japan

Site Status

Site reference ID/Investigator no. ORG-000842

Aichi, , Japan

Site Status

Site reference ID/Investigator # 93736

Aichi, , Japan

Site Status

Research facility ORG-000972

Ehime, , Japan

Site Status

Mylan investigational site A

Hyōgo, , Japan

Site Status

Site reference ID/Investigator # 93735

Ibaraki, , Japan

Site Status

Site Reference ID/Investigator# 88673

Ibaraki, , Japan

Site Status

Site Reference ID/Investigator# 65529

Ishikawa, , Japan

Site Status

Site Reference ID/Investigator# 65530

Kagawa, , Japan

Site Status

Site Reference ID/Investigator# 65527

Kagoshima, , Japan

Site Status

Mylan investigational site C

Kanagawa, , Japan

Site Status

Site Reference ID/Investigator# 65528

Miyagi, , Japan

Site Status

Mylan investigational site B

Miyagi, , Japan

Site Status

Research facility ID ORG-000594

Osaka, , Japan

Site Status

Research facility ID ORG-001138

Ōita, , Japan

Site Status

Research facility ORG-000971

Shizuoka, , Japan

Site Status

Site reference ID/Investigator# 117495

Tochigi, , Japan

Site Status

Research facility no. ORG-001309

Tokyo, , Japan

Site Status

Site Reference ID/Investigator# 67122

Tokyo, , Japan

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Japan

Provided Documents

Download supplemental materials such as informed consent forms, study protocols, or participant manuals.

Document Type: Study Protocol

View Document

Document Type: Statistical Analysis Plan

View Document

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

P12-893

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Fat Malabsorption in Chronic Pancreatitis
NCT02849704 COMPLETED PHASE2
Creon After Pancreatic Surgery
NCT00535756 COMPLETED PHASE4
Phase III ALTU-135 CP Safety Trial
NCT00500084 TERMINATED PHASE3
Effect of Acetyl-L-carnitine on Chronic Pancreatitis
NCT02538146 TERMINATED EARLY_PHASE1