Using Rapid Cine-MRI for Monitoring Moving and Deforming Tumors

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

17 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-09-30

Study Completion Date

2015-11-25

Brief Summary

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In this study, the researchers investigate the feasibility of using rapid cine MR imaging to provide both offline and online soft-tissue-based image guidance. Such images will provide a significantly more complete picture of the spatial and temporal changes in thoracic anatomy. This more complete information will lay the groundwork for better radiotherapy planning and dose delivery in the presence of respiratory motion.

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Detailed Description

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Rapid MRI scans from Stage I-IV non-small-cell lung cancer (NSCLC) patients will be acquired. MR acquisition will be performed without extrinsically administered contrast, using a balanced turbo field echo (TFE) sequence and commercially available coils.

Conditions

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Lung Cancer

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Cine-MRI

Rapid Cine-MRI

Group Type OTHER

cine MRI

Intervention Type OTHER

Rapid Cine-MRI for Monitoring Moving and Deforming Tumors

Interventions

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cine MRI

Rapid Cine-MRI for Monitoring Moving and Deforming Tumors

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* AJCC Stage I, II, III or IV non-small-cell lung cancer to be treated using radiotherapy will be eligible for this study.
* Any types and amounts of prior therapy will be allowed for this study.
* Subjects must be greater than or equal to 18 years of age. There are no gender or ethnic restrictions.
* Ability to understand and the willingness to sign a written informed consent document.
* Able to tolerate supine position
* ECOG performance status of 3 or less

Exclusion Criteria

* MRI-incompatible metallic implants, embedded metallic objects, implanted biomedical devices e.g., cardiac pacemakers
* Women who are pregnant or trying to get pregnant
* Pain in supine position

Minimum Eligible Age

18 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No