Effects of Unilateral WBV on Muscleactivity of Contralateral Hip Adductor

NCT ID: NCT01419782

Last Updated: 2013-05-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-03-31

Study Completion Date

2012-12-31

Brief Summary

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The aim of this study is to investigate effects of femur exposed to unilateral vibration on the rest muscle electrical activity of contralateral hip adductors and contralateral soleus H-reflex in young adult men.

This study hypothesize that femur exposed to unilateral vibration may affect the rest muscle electrical activity of contralateral hip adductors. Vibration can effectively enhance muscle strength and power. Previous studies have shown that vibration increases muscle electromyographic (EMG) activity. It has been showed that bone has an effect on the increase in muscle EMG activity caused by vibration in healthy young adults in a study. In this study, it was reported that vibrations-induced increases in muscle electrical activity of flexor carpi radialis (FCR) was related to ultradistal radius bone mineral content (BMC) and the FCR H-reflex was suppressed or depressed during vibration. This findings were reported to support the assumption that the bone exposed to cyclic mechanical loading may neuronally regulate muscle activity.

Detailed Description

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A total of 20 voluntaries are planned to include in this study.

Vibration will be applied the right lower extremity by whole-body vibration (PowerPlate Pro). Cases will stand on vibration plate. WBV will be applied at a frequency of 40 Hz and amplitude of 2 mm for 60 seconds. WBV will be applied one session only.

The rest muscle electrical activity of ipsilateral and contralateral hip adductor muscles at rest will be measured by PowerLab (data acquisition system, ADInstruments, Australia) device.The rest-EMGrms will be measured at before and during vibration. We also evaluate a change in contralateral soleus H reflex during vibration.

Effects of bone on the rest muscle electrical activity will be assessed by hip bone mineral density, bone mineral content and serum sclerostin level. The right hip bone mineral density (BMD) and BMC will be evaluated by bone densitometer (Norland). Plasma sclerostin level will be measured by using Human Sclerostin ELISA kıt before and after vibration.

Conditions

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Bone Mass Effects of Vibration

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Whole-body vibration

whole body vibration will be applied the right lower limb.

Group Type EXPERIMENTAL

Whole-body vibration

Intervention Type OTHER

Frequency: 40 Hz, vibration amplitude: 2 mm, duration: 60 sec

Interventions

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Whole-body vibration

Frequency: 40 Hz, vibration amplitude: 2 mm, duration: 60 sec

Intervention Type OTHER

Other Intervention Names

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Cyclic mechanical loading

Eligibility Criteria

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Inclusion Criteria

* Age: 20-40 yrs
* Gender: Male
* Volunteer
* Healthy status: Patients having hypoesthesia in his leg and Healthy subjects
* Dominant hand:Right-handed

Exclusion Criteria

* Bone diseases (osteoporosis, osteomalacia, paget's disease, neoplasm, etc),
* Systemic diseases (cardiovascular, endocrine, infections etc),
* Myopathy-tendinopathy
* Lower limb joint disease
* Vertigo
* Obesity (BMI \>30 kg/m2)
* Professional sportsman
* Male doing regular sports activities
* Skin disease in lower limb
* Non-cooperative subject
* Hemolysis of blood sample
Minimum Eligible Age

20 Years

Maximum Eligible Age

40 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Bagcilar Training and Research Hospital

OTHER_GOV

Sponsor Role lead

Responsible Party

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Ilhan Karacan, Clinical Associated Professor

ILHAN KARACAN

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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ILHAN KARACAN, MD

Role: PRINCIPAL_INVESTIGATOR

Bagcilar Training & Research Hospital

Locations

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Bagcilar Training & Research Hospital

Istanbul, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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BEAH FTR-5

Identifier Type: -

Identifier Source: org_study_id

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