The Metabolic Effects of Breaks in Sedentary Time

NCT ID: NCT01398059

Last Updated: 2019-07-24

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 19 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2011-07-31
• Study Completion Date: 2012-08-31

Brief Summary

The purpose of this study is to determine whether acute bouts of sedentary behaviour (with or without breaks and/or structured physical activity) result in measurable changes in metabolic health in children and youth.

Detailed Description

North American children spend the majority of their waking hours engaging in sedentary behavior (e.g. sitting). Research in adults and animal models suggests that even short bouts of uninterrupted siting may result in acute changes increases in cardiometabolic risk, although to date no studies have investigated this relationship in children and youth. The purpose of this study is to assess the feasibility of a protocol which will expose participants aged 10-14 years to a full day of uninterrupted sitting, and to determine the impact of this protocol on markers of cardiometabolic risk (insulin, glucose, triglyceride, HDL-C and LDL-C) as well as subsequent food intake and physical activity. The impact of uninterrupted sitting will be compared to the impact of interrupted sitting, with and without the inclusion of moderate physical activity.

Conditions

Feasibility; Insulin; Glucose; Lipids; Eating

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: CROSSOVER
• Primary Study Purpose: BASIC_SCIENCE
• Blinding Strategy: NONE

Study Groups

Sedentary

In this condition, participants will engage in 8 hours of uninterrupted sedentary behaviour.

Group Type: EXPERIMENTAL

Sedentary

Intervention Type: OTHER

In this condition, participants will engage in 8 hours of uninterrupted sedentary behaviour.

Sedentary With Breaks

In this condition participants will engage in 8 hours of sitting, although the sitting will be interrupted every 20 minutes. During these interruptions participants will spend 2 minutes walking at an intensity equivalent to 30% of VO2peak.

Group Type: EXPERIMENTAL

Sedentary With Breaks

Intervention Type: OTHER

In this condition participants will engage in 8 hours of sitting, although the sitting will be interrupted every 20 minutes. During these interruptions participants will spend 2 minutes walking at an intensity equivalent to 30% of VO2peak.

Sedentary With Breaks and Physical Activity

In this condition participants will engage in 8 hours of sitting, although the sitting will be interrupted every 20 minutes. During these interruptions participants will spend 2 minutes walking at an intensity equivalent to 30% of VO2peak. Participants will also engage in 20 minutes of structured physical activity at an intensity of 60% of VO2peak in both the morning and afternoon.

Group Type: EXPERIMENTAL

Sedentary With Breaks and Physical Activity

Intervention Type: OTHER

In this condition participants will engage in 8 hours of sitting, although the sitting will be interrupted every 20 minutes. During these interruptions participants will spend 2 minutes walking at an intensity equivalent to 30% of VO2peak. Participants will also engage in 20 minutes of structured physical activity at an intensity of 60% of VO2peak in both the morning and afternoon.

Interventions

Sedentary

In this condition, participants will engage in 8 hours of uninterrupted sedentary behaviour.

Intervention Type: OTHER

Sedentary With Breaks

In this condition participants will engage in 8 hours of sitting, although the sitting will be interrupted every 20 minutes. During these interruptions participants will spend 2 minutes walking at an intensity equivalent to 30% of VO2peak.

Intervention Type: OTHER

Sedentary With Breaks and Physical Activity

In this condition participants will engage in 8 hours of sitting, although the sitting will be interrupted every 20 minutes. During these interruptions participants will spend 2 minutes walking at an intensity equivalent to 30% of VO2peak. Participants will also engage in 20 minutes of structured physical activity at an intensity of 60% of VO2peak in both the morning and afternoon.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Age 10-14
• Normal weight or obese

Exclusion Criteria

• Overweight
• Overt diabetes or heart disease (or taking medications to treat this conditions)
• Being unambulatory or otherwise unable to perform the study protocol

• Minimum Eligible Age: 10 Years
• Maximum Eligible Age: 14 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

University of Ottawa

OTHER

Sponsor Role: collaborator

Children's Hospital of Eastern Ontario

OTHER

Sponsor Role: lead

Responsible Party

Mark Tremblay

Dr Mark Tremblay, Director, Healthy Active Living and Obesity Research Group

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Mark S Tremblay, OhD

Role: PRINCIPAL_INVESTIGATOR

Children's Hospital of Eastern Ontario Research Institute

Locations

Behavioural Metabolic Research Unit, University of Ottawa

Ottawa, Ontario, Canada

Countries

Canada

References

Saunders TJ, Chaput JP, Goldfield GS, Colley RC, Kenny GP, Doucet E, Tremblay MS. Prolonged sitting and markers of cardiometabolic disease risk in children and youth: a randomized crossover study. Metabolism. 2013 Oct;62(10):1423-8. doi: 10.1016/j.metabol.2013.05.010. Epub 2013 Jun 15.

Reference Type: RESULT

PMID: 23773981 (View on PubMed)

Other Identifiers

11/01E

Identifier Type: -

Identifier Source: org_study_id