IMproved PREdiction of Severe Sepsis in the Emergency Department

NCT ID: NCT01392508

Last Updated: 2017-04-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

759 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-03-31

Study Completion Date

2015-09-30

Brief Summary

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The purposes of this study is to determine whether Heparin Binding Protein (HBP) can be used as a marker of severe sepsis (including septic shock) in patients presenting to the emergency department with suspected infection.

Detailed Description

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Conditions

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Systemic Inflammatory Response Syndrome (SIRS) Sepsis Severe Sepsis Septic Shock

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Greater than or equal to 18 years
* Suspected Infection
* one or more SIRS criteria
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Axis Shield Diagnostics Ltd

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Adam Linder

Role: PRINCIPAL_INVESTIGATOR

Skanes Universitetssjukhus I Lund, Sweden

Magnus Paulsson

Role: PRINCIPAL_INVESTIGATOR

Skanes universitetssjukhuset i Malmo

Patrik Nyberg

Role: PRINCIPAL_INVESTIGATOR

Universitetssjukhuset i Linkoping

Anna Lange-Jendeberg

Role: PRINCIPAL_INVESTIGATOR

Universitetssjukhuset i Orebro

Ryan Arnold

Role: PRINCIPAL_INVESTIGATOR

The Cooper Health System

Locations

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Cooper University Hospital

Camden, New Jersey, United States

Site Status

Universitetssjukhuset i Linkoping

Linköping, , Sweden

Site Status

Skanes Universitetssjukhus i Lund

Lund, , Sweden

Site Status

Skanes Universitetssjukhuset i Malmo

Malmo, , Sweden

Site Status

Universitetssjukhuset i Orebro

Örebro, , Sweden

Site Status

Countries

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United States Sweden

References

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Linder A, Arnold R, Boyd JH, Zindovic M, Zindovic I, Lange A, Paulsson M, Nyberg P, Russell JA, Pritchard D, Christensson B, Akesson P. Heparin-Binding Protein Measurement Improves the Prediction of Severe Infection With Organ Dysfunction in the Emergency Department. Crit Care Med. 2015 Nov;43(11):2378-86. doi: 10.1097/CCM.0000000000001265.

Reference Type RESULT
PMID: 26468696 (View on PubMed)

Other Identifiers

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PEP-FMHBP-001

Identifier Type: -

Identifier Source: org_study_id

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