Transcranial Direct Current Stimulation (tDCS) for Treatment of Negative Syndrome in Patients With Schizophrenia

NCT ID: NCT01378078

Last Updated: 2013-07-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-06-30

Study Completion Date

2013-06-30

Brief Summary

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Transcranial direct current stimulation (tDCS) showed beneficial effects on cognition in healthy subjects and depressed patients. In this study, patients with treatment resistant negative syndrome in schizophrenia will be treated with direct current stimulation. fMRI measures will be performed.

Detailed Description

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Conditions

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Schizophrenia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Caregivers

Study Groups

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sham

patients receive sham tDCS stimulation

Group Type SHAM_COMPARATOR

eldith DC-stimulator (neuroconn, Ilmenau, Germany)

Intervention Type DEVICE

daily tDCS treatment over left DLPFC, 20 min, 2 mA

active

active transcranial direct current stimulation

Group Type ACTIVE_COMPARATOR

eldith DC-stimulator (Neuroconn, Ilmenau, Germany)

Intervention Type DEVICE

same as sham stimulation

Interventions

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eldith DC-stimulator (neuroconn, Ilmenau, Germany)

daily tDCS treatment over left DLPFC, 20 min, 2 mA

Intervention Type DEVICE

eldith DC-stimulator (Neuroconn, Ilmenau, Germany)

same as sham stimulation

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* schizophrenic patients with a negative syndrome. PANSS \> 40.

Exclusion Criteria

* other psychiatric or neurologic diseases.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ludwig-Maximilians - University of Munich

OTHER

Sponsor Role lead

Responsible Party

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Daniel Keeser

Ph.D.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ulrich Palm, MD

Role: PRINCIPAL_INVESTIGATOR

Ludwig Maximilian University Munich

Locations

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Klinik fuer Psychiatrie

Munich, , Germany

Site Status

Countries

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Germany

Other Identifiers

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04/2011

Identifier Type: -

Identifier Source: org_study_id

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