Effect of Aspirin at the Acute Phase of Cerebral Ischemic Event.

NCT ID: NCT01375400

Last Updated: 2011-06-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-12-31

Brief Summary

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Aspirin is the only anti-platelet medication used at the acute phase of ischemic stroke. The investigators would like to study laboratory effect of the first oral 300 mg dose of aspirin, given at hospital, after an ischemic event.

The principal hypothesis is that platelet activity would be able to recover during this day and could lead to ischemic recurrences.

Two blood samples are accomplished. The first 2 hours after aspirin intake and the second 23 hours after. Photometric aggregometry are performed with arachidonic acid and collagen induced platelet aggregation, measure of thromboxan B2 levels and reticular platelets count.

Detailed Description

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Conditions

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Ischemic Stroke

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Interventions

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Aspirin

Administration of 300 mg of aspirin, per os.

Intervention Type DRUG

blood sample

2 blood samples will be performed

Intervention Type BIOLOGICAL

Eligibility Criteria

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Inclusion Criteria

* Adult men and women
* Ischemic stroke less than 48 hours
* Signed consent

Exclusion Criteria

* Danger to prescription of aspirin (haemorrhagic risk...)
* Prescription of heparin or VKA
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Central Hospital, Nancy, France

OTHER

Sponsor Role lead

Responsible Party

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CentralHNF

Locations

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Hopital central

Nancy, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Sébastien Richard, MD

Role: CONTACT

3 83 85 16 56 ext. 0 33

Facility Contacts

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Sébastien Richard, MD

Role: primary

3 83 85 16 56 ext. 33 0

Other Identifiers

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Aspirin

Identifier Type: -

Identifier Source: org_study_id

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