Study of the Natural History of FFR Guided Percutaneous Coronary Intervention
NCT ID: NCT01366404
Last Updated: 2024-11-14
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
20000 participants
OBSERVATIONAL
2011-06-30
2037-04-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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FFR
Patients who had FFR measurement
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* FFR measurement on one and more coronary artery stenosis
* Willing and able to provide informed, written consent
Exclusion Criteria
* Graft vessel
* Ejection fraction \< 30%
* Angiographic evidence of extreme tortuosity or calcified coronary vessels
* Suspected coronary spasm even after sufficient nitrate injected
* Life expectancy \<2 year
* Planned cardiac surgery or planned major non cardiac surgery
* Woman who are breastfeeding, pregnant or planning to become pregnant during the course of the study
* visually-estimated angiographic reference segment diameter of \<2.75mm or \>4.0mm
* Inappropriate for IVUS/VH/OCT procedures : inability for imaging wire or catheter to pass through the tight stenosis, severe calcification, angulation
35 Years
ALL
No
Sponsors
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CardioVascular Research Foundation, Korea
OTHER
Abbott Medical Devices
INDUSTRY
Seung-Jung Park
OTHER
Responsible Party
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Seung-Jung Park
Professor, Division of Cardiology
Principal Investigators
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Seung-Jung Park, MD,PhD
Role: PRINCIPAL_INVESTIGATOR
Asan Medical Center
Locations
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Hallym University Sacred Heart Hospital
Anyang, , South Korea
Soon Chun Hyang University Hospital Bucheon
Bucheon-si, , South Korea
Chungbuk National University Hospital
Cheongju-si, , South Korea
Gangwon National Univ. Hospital
Chuncheon, , South Korea
Daegu Catholic University Center
Daegu, , South Korea
Keimyung University Dongsan Medical Center
Daegu, , South Korea
Kyungpook National university hospital
Daegu, , South Korea
Yeungnam University Medical Center
Daegu, , South Korea
Chungnam National University Hospital
Daejeon, , South Korea
The Catholic University of Korea, Deajeon St.Mary's hospital
Daejeon, , South Korea
Gangneung Asan Hospital
Gangneung, , South Korea
Chonnam National University Hospital
Gwangju, , South Korea
Inje University Ilsan Paik Hospital
Ilsan, , South Korea
Dong-A Medical Center
Pusan, , South Korea
Pusan National University Hospital
Pusan, , South Korea
Seoul university Bundang hospital
Seongnam, , South Korea
Asan Medical Center
Seoul, , South Korea
Gangnam Severance Hospital
Seoul, , South Korea
Hallym University Kangdong Sacred Heart Hospital
Seoul, , South Korea
Korea University Anam Hospital
Seoul, , South Korea
Korea University Guro Hospital
Seoul, , South Korea
Kyung-Hee University Hospital at Kangdong
Seoul, , South Korea
Seoul National University Boramae Medical Center
Seoul, , South Korea
Seoul National University Hospital
Seoul, , South Korea
The Catholic University of Korea, Seoul St.Mary's Hospital
Seoul, , South Korea
The Catholic University of Korea, Yeouido St. Mary's Hospital
Seoul, , South Korea
Ulsan University Hospital
Ulsan, , South Korea
Wonju Severance Christian Hospital
Wŏnju, , South Korea
Pusan National University Yangsan Hospital
Yangsan, , South Korea
Countries
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Central Contacts
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Facility Contacts
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Hyun-sook Kim, MD
Role: primary
Nae-hee Lee, MD
Role: primary
Sang-yeub Lee, MD
Role: primary
Bong-ki Lee, MD
Role: primary
Bong-ki Kim, MD
Role: backup
Jin-bae Lee, MD
Role: primary
Chang-wook Nam, MD
Role: primary
Hun-sik Park, MD
Role: primary
Jong-seon Park, MD
Role: primary
Si-wan Choi, MD
Role: primary
Sung-ho Her, MD
Role: primary
Sang-sig Jung, MD
Role: primary
Young-jun Hong, MD
Role: primary
Joon-hyung Doh, MD
Role: primary
Kyung-il Park, MD
Role: primary
Taeg-jong Hong, MD
Role: primary
In-ho Chae, MD
Role: primary
Seung-jung Park, MD
Role: backup
Byoung-kwon Lee, MD
Role: primary
Kyoo-rok Han, MD
Role: primary
Do-sun Lim, MD
Role: primary
Seung-un Na, MD
Role: primary
Jong-jin Kim, MD
Role: primary
Woo-young Chung, MD
Role: primary
Bon-kwon Koo, MD
Role: primary
Ki-bae Seung, MD
Role: primary
Chul-soo Park, MD
Role: primary
Eun-seok Shin, MD
Role: primary
Jung-han Yoon, MD
Role: primary
Jun-hong Kim, MD
Role: primary
References
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Ahn JM, Park DW, Kim SO, Kang DY, Lee CH, Lee PH, Lee SW, Park SW, Park SJ. Prognostic Value of Resting Distal-to-Aortic Coronary Pressure in Clinical Practice. Circ Cardiovasc Interv. 2020 May;13(5):e007868. doi: 10.1161/CIRCINTERVENTIONS.118.007868. Epub 2020 Apr 29.
Kang DY, Ahn JM, Kim YW, Moon JY, Lee JS, Koo BK, Lee PH, Park DW, Kang SJ, Lee SW, Kim YH, Park SW, Park SJ. Impact of Coronary Lesion Geometry on Fractional Flow Reserve: Data From Interventional Cardiology Research In-Cooperation Society-Fractional Flow Reserve and Intravascular Ultrasound Registry. Circ Cardiovasc Imaging. 2018 Jun;11(6):e007087. doi: 10.1161/CIRCIMAGING.117.007087.
Kang DY, Ahn JM, Lee CH, Lee PH, Park DW, Kang SJ, Lee SW, Kim YH, Lee CW, Park SW, Park SJ. Deferred vs. performed revascularization for coronary stenosis with grey-zone fractional flow reserve values: data from the IRIS-FFR registry. Eur Heart J. 2018 May 7;39(18):1610-1619. doi: 10.1093/eurheartj/ehy079.
Lee JM, Hwang D, Park J, Zhang J, Tong Y, Kim CH, Bang JI, Suh M, Paeng JC, Cheon GJ, Koo BK. Exploring Coronary Circulatory Response to Stenosis and Its Association With Invasive Physiologic Indexes Using Absolute Myocardial Blood Flow and Coronary Pressure. Circulation. 2017 Nov 7;136(19):1798-1808. doi: 10.1161/CIRCULATIONAHA.117.029911. Epub 2017 Aug 29.
Ahn JM, Park DW, Shin ES, Koo BK, Nam CW, Doh JH, Kim JH, Chae IH, Yoon JH, Her SH, Seung KB, Chung WY, Yoo SY, Lee JB, Choi SW, Park K, Hong TJ, Lee SY, Han M, Lee PH, Kang SJ, Lee SW, Kim YH, Lee CW, Park SW, Park SJ; IRIS-FFR Investigatorsdagger. Fractional Flow Reserve and Cardiac Events in Coronary Artery Disease: Data From a Prospective IRIS-FFR Registry (Interventional Cardiology Research Incooperation Society Fractional Flow Reserve). Circulation. 2017 Jun 6;135(23):2241-2251. doi: 10.1161/CIRCULATIONAHA.116.024433. Epub 2017 Mar 29.
Lee JM, Kim CH, Koo BK, Hwang D, Park J, Zhang J, Tong Y, Jeon KH, Bang JI, Suh M, Paeng JC, Cheon GJ, Na SH, Ahn JM, Park SJ, Kim HS. Integrated Myocardial Perfusion Imaging Diagnostics Improve Detection of Functionally Significant Coronary Artery Stenosis by 13N-ammonia Positron Emission Tomography. Circ Cardiovasc Imaging. 2016 Sep;9(9):e004768. doi: 10.1161/CIRCIMAGING.116.004768.
Kang SJ, Ahn JM, Han S, Lee JY, Kim WJ, Park DW, Lee SW, Kim YH, Lee CW, Park SW, Mintz GS, Park SJ. Sex differences in the visual-functional mismatch between coronary angiography or intravascular ultrasound versus fractional flow reserve. JACC Cardiovasc Interv. 2013 Jun;6(6):562-8. doi: 10.1016/j.jcin.2013.02.016.
Park SJ, Kang SJ, Ahn JM, Shim EB, Kim YT, Yun SC, Song H, Lee JY, Kim WJ, Park DW, Lee SW, Kim YH, Lee CW, Mintz GS, Park SW. Visual-functional mismatch between coronary angiography and fractional flow reserve. JACC Cardiovasc Interv. 2012 Oct;5(10):1029-36. doi: 10.1016/j.jcin.2012.07.007.
Other Identifiers
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CVRF2010-09
Identifier Type: -
Identifier Source: org_study_id
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