Adjunctive Photodynamic Therapy in the Treatment of Chronic Periodontitis

NCT ID: NCT01330082

Last Updated: 2011-04-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE2/PHASE3

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-04-30

Study Completion Date

2011-05-31

Brief Summary

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The aim of this randomized clinical trial is to clinically evaluate the effectiveness of the adjunctive use of photodynamic therapy (PDT) with an light-emitting diode (LED) light source in the treatment of chronic periodontitis.

Detailed Description

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Conditions

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Chronic Periodontitis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Photodynamic therapy

will be treated by PDT using Light-emitting diod(LED) (625-635nm,200mw/cm2 ,30 s for each site, fotoson CMS Dental ,Denmark) in the presence of toluidine blue O (TBO)

Group Type EXPERIMENTAL

Adjunctive Photodynamic Therapy

Intervention Type OTHER

using Light-emitting diod(LED) (625-635nm,200mw/cm2 ,30 s for each site, fotoson CMS Dental ,Denmark) in the presence of toluidine blue O (TBO)

Light-emitting diode Irradiation

will be treated only by using Light-emitting diode(LED) (625-635nm,200mw/cm2 ,30 s for each site, fotoson CMS Dental ,Denmark)

Group Type EXPERIMENTAL

Light-emitting diod Irradiation

Intervention Type OTHER

625-635nm,200mw/cm2 ,30 s for each site, fotoson CMS Dental ,Denmark

applying photosensitizer

will be treated only by toluidine blue O

Group Type EXPERIMENTAL

applying Photosensitizer

Intervention Type OTHER

toluidine blue O is applied at the bottom of each periodontal pocket

Interventions

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Adjunctive Photodynamic Therapy

using Light-emitting diod(LED) (625-635nm,200mw/cm2 ,30 s for each site, fotoson CMS Dental ,Denmark) in the presence of toluidine blue O (TBO)

Intervention Type OTHER

Light-emitting diod Irradiation

625-635nm,200mw/cm2 ,30 s for each site, fotoson CMS Dental ,Denmark

Intervention Type OTHER

applying Photosensitizer

toluidine blue O is applied at the bottom of each periodontal pocket

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. clinically diagnosis of advanced chronic periodontitis with more than 3 mm clinical attachment loss
2. presence of at least two teeth with probing depth of 4 to 6 mm without furcation involvement in each quadrant
3. at least 16 remaining teeth
4. no periodontal treatment in the past 12 months
5. no evidence of systemic disease related to periodontal problems
6. no use of antibiotics for the past 6 months
7. No smoking more than 10 cigarettes per day
8. no addiction to any kind of drugs
9. no pregnancy
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Tehran University of Medical Sciences

OTHER

Sponsor Role lead

Responsible Party

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Tehran University of Medical Sciences

Principal Investigators

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Neda Moslemi, DDS,MS

Role: STUDY_CHAIR

Tehran University of Medical Sciences

Seyed Hossein Bassir, DDS

Role: PRINCIPAL_INVESTIGATOR

Tehran University of Medical Sciences

Locations

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Tehran University of Medical Sciences

Tehran, Tehran Province, Iran

Site Status

Countries

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Iran

Other Identifiers

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09123209916

Identifier Type: -

Identifier Source: org_study_id

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