Accommodation Disorders

NCT ID: NCT01329848

Last Updated: 2015-01-05

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 83 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2010-12-31
• Study Completion Date: 2013-08-31

Brief Summary

This project will develop clinically useful, objective measurements of accommodative insufficiency and fatigue using continuous autorefraction recordings. The development of these procedures will help vision care professionals diagnose and treat accommodative anomalies.

Detailed Description

This project studies accommodative function, the ability to focus while doing near work. Visual discomfort symptoms, such as headaches, sore eyes, and blurred vision are commonly associated with prolonged reading or other near work. Researchers have long suspected accommodative dysfunction was involved but most clinical studies have failed to establish a relationship between weak accommodation and symptoms or reading impairments. Recent research, however, has found that clinical measure overestimate accommodative function and encourage the use of objective, autorefraction methods to measure and study accommodative weakness. This project will accomplish three goals. First, using autorefraction objective reliable procedures will be developed for measuring accommodative lag, the difference between the target location and where the eye is focused. Second, experiments will measure in real-time the impact of accommodative lag on reading fluency and visual discomfort systems. Third, studies will explore the role of the slow adaptive component in accommodative weakness. This work will lead to better methods for diagnosing and treating accommodative disorders.

Conditions

Accommodative Insufficiency; Ill-sustained Accommodation

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

discomfort symptoms

level of discomfort symptoms while performing near work

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• older adolescent and young adult
• skilled readers who attend school
• are skilled readers
• have heavy reading demands

Exclusion Criteria

• Age > 30.
• Abnormal vergence system.
• Dry-eye.
• Uncorrected visual defects or significant ocular pathology.
• Learning disability or low IQ
• Medical conditions that might cause uncomfortable visual symptoms (e.g., migraine headaches, epilepsy, head trauma); sensory defects (e.g., deafness), or neurological conditions (e.g., stuttering) that could impair reading development or oral reading fluency.
• Somatosensory amplification.
• Systemic illness or medication associated with accommodative dysfunction.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 30 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Southern California College of Optometry at Marshall B. Ketchum University

OTHER

Sponsor Role: collaborator

Western University of Health Sciences

OTHER

Sponsor Role: lead

Responsible Party

Christopher Chase

Professor of Optometry

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Chris Chase, PhD

Role: PRINCIPAL_INVESTIGATOR

Western University of Health Sciences

Locations

Western University of Health Sciences

Pomona, California, United States

Countries

United States

Other Identifiers

1R15EY021021

Identifier Type: NIH

Identifier Source: org_study_id

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