Staging Candidiasis in ICU Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

422 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-10-31

Study Completion Date

2014-10-07

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Our primary objective is to evaluate the relevance of the early determination of Candida infection status among non-neutropenic patients hospitalized over 48 hours in ICUs.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Antifungal Prophylaxis in Intensive Care Unit (ICU) Patients

NCT01495039

Fungal Prophylaxis Candida Infection Critical Illness +1 more

COMPLETED PHASE4

Characterization of Fungal Infections in COVID-19 Infected and Mechanically Ventilated Patients in ICU

NCT04368221

Covid-19

COMPLETED

Performance of Clinical and Biological Diagnostic Tests in Reference to the Recommended Tests for the Management of Fungal Peritonitis in Intensive Care

NCT03973645

Peritonitis

COMPLETED

Invasive Candidiasis in Saudi ICUs

NCT01490684

Invasive Candidiasis

COMPLETED

Nosocomial Bacterial and Fungal Chest Infections in Cirrhotic Patients

NCT03413293

Nosocomial Infection

UNKNOWN

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Candidiasis

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

The study population

The target population includes patients in ICUs at the Nîmes and Montpellier University hospitals. This is a population of non-neutropenic patients (polynuclear neutrophils \> 500/mm3) at risk of developing invasive candidiasis.

Tests for candidiasis

Intervention Type BIOLOGICAL

Tests include (1) anti-candida antibody ELISA kit; (2) candida antigen ELISA kit; (3) detection of circulating Candida DNA via SYBR Breen qPCR Master mix; (4) colonization index based on mycological examination of five out of the following: urine, oral swab, bronchial aspirate, anal swab, swab of a central venous line, gastric liquid.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Tests for candidiasis

Tests include (1) anti-candida antibody ELISA kit; (2) candida antigen ELISA kit; (3) detection of circulating Candida DNA via SYBR Breen qPCR Master mix; (4) colonization index based on mycological examination of five out of the following: urine, oral swab, bronchial aspirate, anal swab, swab of a central venous line, gastric liquid.

Intervention Type BIOLOGICAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Polynuclear neutrophils \> 500/mm\^3
* Hospitalized for \> 48 hours in participating ICUs

Exclusion Criteria

* Patients discharged from ICU in \< 48h
* Patient diagnosed with invasive candidosis before entry to ICU
* Patient is taking an anti-fungal treatment
* polynuclear neutrophils \< 500/mm\^3
* patient transferred to another ICU
* patient included in the Abmidex protocole

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No