The Role of FGF23 and Asymmetric Dimethylarginine (ADMA) in Chronic Kidney Disease

NCT ID: NCT01317186

Last Updated: 2011-03-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-03-31

Brief Summary

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In chronic kidney disease calcium (Ca) and phosphate (P) metabolism disorders are very common and also they are one of the leading causes of morbidity in these population. FGF23 is a novel factor that contributes Ca-P disorders. It has been hypothesized that FGF 23 increase is mediated by asymmetric dimethylarginine (ADMA). The aim of the study is to evaluate this hypothesis.

Detailed Description

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Conditions

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Metabolic Diseases Chronic Kidney Disease

Study Design

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Observational Model Type

COHORT

Study Groups

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Group I

Stage 2 Non-diabetic Chronic Kidney Disease

No interventions assigned to this group

Group II

Stage 3 Non-diabetic Chronic Kidney Disease

No interventions assigned to this group

Group III

Stage 4 Non-diabetic Chronic Kidney Disease

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* between ages of 18 - 65 years old
* chronic kidney disease of stage 2-4

Exclusion Criteria

* presence of diabetes mellitus or ischemic hearth disease
* taking vitamin d therapy
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ankara Education and Research Hospital

OTHER_GOV

Sponsor Role lead

Responsible Party

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Ankara Education and Research Hospital

Locations

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Ankara Education and Research Hospital

Ankara, , Turkey (Türkiye)

Site Status RECRUITING

Countries

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Turkey (Türkiye)

Facility Contacts

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Alper AZAK

Role: primary

Bülent Huddam

Role: backup

Other Identifiers

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NEPH002

Identifier Type: -

Identifier Source: org_study_id

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