Clinical Evaluation of a Normoproteic Diet

NCT ID: NCT01303289

Last Updated: 2011-02-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-02-28

Study Completion Date

2007-12-31

Brief Summary

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The main objective of this trial is the clinical evaluation of a normoproteic diet, when this diet is used for total enteral nutrition in geriatric people.

For 3 months,all the participants in the study will receive only tube feeding: The experimental group will receive the commercial preparation to evaluate (T-Diet Plus ®, Vegenat SA) and the control group will receive a standard diet (Jevity ®, Abbott Laboratories).

Detailed Description

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The project includes:

* Product tolerance study: gastrointestinal and metabolic complications related to the product administration.
* The monitoring of the intervention, and clinical and nutritional evaluation of the participants, including anthropometry, quality of life related to the health and clinical and nutritional status analytical evaluation (hematology and biochemistry).
* The determination of the major biochemical variables related to the lipid profile and assessment of the antioxidant defense system, and also certain markers of metabolic syndrome and associated cardiovascular risk.

Conditions

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Severe Insufficient Nutrition

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

SINGLE

Participants

Study Groups

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Group 1

The group 1 will receive the experimental product T-Diet plus Standard for 3 months.

Group Type EXPERIMENTAL

T-Diet plus Standard

Intervention Type DIETARY_SUPPLEMENT

T-Diet plus Standard is a complete balanced protein and energy oral nutrition supplement, indicated for the dietary management of patients with related malnutrition.

Group 2

The group 2 will receive the control product Jevity (Abbott Laboratories) for 3 months.

Group Type ACTIVE_COMPARATOR

Jevity

Intervention Type DIETARY_SUPPLEMENT

JEVITY is a diet for tube-fed patients in the medium to long term, to varying degrees of malnutrition with gastrointestinal disorders.

Interventions

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T-Diet plus Standard

T-Diet plus Standard is a complete balanced protein and energy oral nutrition supplement, indicated for the dietary management of patients with related malnutrition.

Intervention Type DIETARY_SUPPLEMENT

Jevity

JEVITY is a diet for tube-fed patients in the medium to long term, to varying degrees of malnutrition with gastrointestinal disorders.

Intervention Type DIETARY_SUPPLEMENT

Other Intervention Names

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TDP STD JEV ABBT

Eligibility Criteria

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Inclusion Criteria

* Patients over 65 years old, of both sex, receiving total enteral nutrition by tube.
* Admitted to medically supervised institutions (homes, health centers).
* Requirement for total enteral nutrition standard, at least 3 months.
* Acceptance volunteer to participate in the study by signing the written informed consent (approved by the Ethics Committee of University Hospital Virgen de las Nieves).

Exclusion Criteria

* Patients who receive drugs with lipid composition.
* Unstable clinical situation.
* Patients with terminal illness.
* Refusal or physical or mental inability to cooperate in the study.
* Participating in another study.
* Other causes: social causes, humanitarian, non-cooperation, etc..
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Vegenat, S.A.

INDUSTRY

Sponsor Role lead

Responsible Party

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VEGENAT, S.A.

Principal Investigators

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Ángel Gil, PhD

Role: PRINCIPAL_INVESTIGATOR

Departament of Biochemistry and Molecular Biology II. University of Granada

Locations

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Department of Biochemistry and Molecular Biology II. University of Granada

Granada, Granada, Spain

Site Status

Countries

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Spain

Other Identifiers

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TDP STANDARD 2006

Identifier Type: OTHER

Identifier Source: secondary_id

VEGENAT-TDP STD UGR

Identifier Type: -

Identifier Source: org_study_id

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