Epidemiology of Barrett's Esophagus: A Population Based Study

NCT ID: NCT01286155

Last Updated: 2013-05-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

534 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-01-31

Study Completion Date

2011-06-30

Brief Summary

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To assess attitudes toward screening for esophageal adenocarcinoma (EAC) and Barrett's esophagus (BE) in the community.

To develop a population based clinical risk factor prediction model for the diagnosis of BE and identify novel risk factors for BE which would make population based screening more efficient. This will be an important first step in identifying the target population for BE screening, another crucial component of making screening feasible and efficient

Detailed Description

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Conditions

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Barrett's Esophagus Gastroesophageal Reflux Disease (GERD) Olmsted County Resident

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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with gastroesophageal reflux disease(GERD)

Subjects with gastroesophageal reflux disease (GERD)

No interventions assigned to this group

Non-GERD

Subjects with no history of gastroesophageal reflux disease (GERD)

No interventions assigned to this group

Barrett's esophagus

Subjects with confirmed barrett's esophagus in Olmsted county

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

1. Case: Olmsted county residents \> 18 years old from the barrett's esophagus (BE) incidence cohort who are still alive at the time of study.
2. Control # 1 : Olmsted county residents \> 18 years old that responded to a recent community based survey and reported gastroesophageal reflux (GER) symptoms at least once a week and without a known diagnosis of BE.
3. Control # 2 : Olmsted county residents \> 18 years old that responded to a recent community based survey that did not report any GER symptoms and without a known diagnosis of BE.

Exclusion Criteria

1. Cases: BE subjects who

1. Have died prior to the start of this study;
2. Refuse to participate;
2. Controls: respondents to the "constipation survey" who

1. Are known to have BE;
2. Have died prior to the start of this study;
3. Refuse to participate; -
Minimum Eligible Age

18 Years

Maximum Eligible Age

95 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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American College of Gastroenterology

OTHER

Sponsor Role collaborator

Mayo Clinic

OTHER

Sponsor Role lead

Responsible Party

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Prasad G. Iyer

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Mayo Clinic

Rochester, Minnesota, United States

Site Status

Countries

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United States

Other Identifiers

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09-002718

Identifier Type: -

Identifier Source: org_study_id

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