SOLX Gold Shunt for Refractory Glaucoma

NCT ID: NCT01282346

Last Updated: 2017-02-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

116 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-01-31

Study Completion Date

2015-12-31

Brief Summary

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To establish the clinical performance of the SOLX Gold Shunt for its ability to reduce intraocular pressure (IOP) in eyes with refractory glaucoma where medical and conventional surgical treatments have failed.

Detailed Description

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Conditions

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Glaucoma Glaucoma, Open Angle

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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SOLX Gold Shunt

Group Type EXPERIMENTAL

SOLX Gold Shunt

Intervention Type DEVICE

Single use implant

Interventions

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SOLX Gold Shunt

Single use implant

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* primary open-angle glaucoma
* age 21 or over
* refractory glaucoma, with IOP ≥ 24 mmHg on medications and failed prior incisional glaucoma surgery
* detectable visual field defect (negative MD score)
* written informed consent
* available for up to 24 months follow-up

Exclusion Criteria

* either eye with VA worse than count fingers
* angle closure glaucoma episode within past 12 months
* uveitic glaucoma, iridocorneal endothelial (ICE) syndrome, traumatic glaucoma, or neovascular glaucoma
* diagnosis of pigmentary glaucoma or pseudoexfoliative glaucoma
* other significant ocular disease, except cataract
* active ocular infection
* expected ocular surgery in next 12 months
* no suitable quadrant for implant
* systemic corticosteroid therapy \> 5 mg/day prednisone
* intolerance to gonioscopy or other eye exams
* mental impairment interfering with consent or compliance
* pregnancy
* known sensitivity to anticipated medications used at surgery
* significant co-morbid disease
* concurrent enrollment in another drug or device study
Minimum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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SOLX, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Nilay Shah, MD

Role: STUDY_DIRECTOR

The Emmes Company, LLC

Locations

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University of Alabama

Birmingham, Alabama, United States

Site Status

Vold Vision, PLLC

Springdale, Arkansas, United States

Site Status

University of California, Irvine

Irvine, California, United States

Site Status

Yale University

New Haven, Connecticut, United States

Site Status

Illinois Eye Institute

Chicago, Illinois, United States

Site Status

Glaucoma Associates of New York

New York, New York, United States

Site Status

Ophthalmic Partners of Pennsylvania

Bala-Cynwyd, Pennsylvania, United States

Site Status

University Eye Surgeons

Maryville, Tennessee, United States

Site Status

Glaucoma Associates of Texas

Dallas, Texas, United States

Site Status

University of Virginia

Charlottsville, Virginia, United States

Site Status

Memmen, Ltd

Green Bay, Wisconsin, United States

Site Status

University of Campinas

Campinas, , Brazil

Site Status

Clarity Eye Institute

Vaughan, Ontario, Canada

Site Status

Institut de l'oeil des Laurentides

Boisbriand, Quebec, Canada

Site Status

Bellevue Ophthalmology Clinic

Montreal, Quebec, Canada

Site Status

Medical Research Infrastructure Department and Health Services Fund by the Sheba Medical Center (R.A.)

Tel Litwinsky, , Israel

Site Status

Centro Medico Docente La Trinidad

Caracas, , Venezuela

Site Status

Countries

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United States Brazil Canada Israel Venezuela

Other Identifiers

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SLX84

Identifier Type: -

Identifier Source: org_study_id

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