Dual-energy CT in Detecting Bone Marrow Edema of Vertebral Compression Fractures
NCT ID: NCT01281826
Last Updated: 2011-02-11
Study Results
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Basic Information
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UNKNOWN
70 participants
OBSERVATIONAL
2011-01-31
2011-12-31
Brief Summary
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1. Assess bone marrow edema within the VCF by use of a DE CT virtual noncalcium image compared with MR imaging as standard reference.
2. Evaluate parameters related to the BME of the collapsed vertebral body on DE CT virtual noncalcium images, such as the morphologic signs, visual qualitative detection, and quantitative values.
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Detailed Description
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The bone marrow edema (BME) in acute/subacute VCFs is useful in determining the vertebra that is to be treated.
MR imaging provides information on anatomic vertebral collapse and the loss of normal T1 high signal intensity from the marrow space of vertebrae with acute fractures. Loss of normal T1 high signal intensity indicates the presence of BME, which is the important sign for the PVP treatment of VCFs.
Dual-energy (DE) CT has been used to create a virtual unenhanced scan by subtracting iodine from contrast agent-enhanced CT examinations.We expect that the same technique can be used to calculate a virtual noncalcium image from an unenhanced image, which makes bone marrow accessible for CT diagnosis.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Pregnancy
* Any contraindications to MR imaging.
18 Years
75 Years
ALL
No
Sponsors
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National Cheng-Kung University Hospital
OTHER
Responsible Party
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National Cheng-Kung University Hospital
Principal Investigators
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Chien-Kuo Wang
Role: STUDY_CHAIR
Department of Diagnostic Radiology Cheng Kung University Medicial Center
Locations
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National Cheng-Kung University Hospital
Tainan City, , Taiwan
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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BR-99-093
Identifier Type: -
Identifier Source: org_study_id
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