Peripheral Facilitated Antegrade Steering Technique in Chronic Total Occlusions

NCT ID: NCT01246505

Last Updated: 2012-07-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

105 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-07-31

Study Completion Date

2012-01-31

Brief Summary

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Study of the BridgePoint Medical System in the crossing of chronic total occlusions of the lower extremities.

Detailed Description

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Conditions

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Chronic Total Occlusion

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Interventions

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CTO Crossing and Percutaneous transluminal angioplasty

Crossing of the CTO with the BridgePoint Medical System and subsequent treatment of the CTO via PTA (specific devices to be used for PTA at investigators' discretion)

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* suitable candidate for non-emergent, peripheral angioplasty
* documented de-novo or restenotic peripheral CTO lesion with TIMI 0 flow for at least 90 days and satisfactory distal vessel visualization (collateral supply)
* limb ischemia or claudication, Rutherford class I-III (grade 1-5) caused by the occluded artery

Exclusion Criteria

* intolerance to aspirin or a neutropenic response to Ticlopidine or Clopidogrel
* appearance of thrombus or intraluminal filling defects
* peripheral intervention in the target limb within two weeks of the procedure
* renal insufficiency (serum creatinine of \> 2.3 mg/dl)
* contraindication to a peripheral artery intervention
* participation in another investigational protocol
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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BridgePoint Medical

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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William A Gray, MD

Role: PRINCIPAL_INVESTIGATOR

Columbia University

Locations

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St. Luke's Medical Center

Phoenix, Arizona, United States

Site Status

University of Southern California Medical Center

Los Angeles, California, United States

Site Status

Torrance Memorial Medical Center

Torrance, California, United States

Site Status

University of Colorado Denver

Denver, Colorado, United States

Site Status

Emory University Medical Center

Atlanta, Georgia, United States

Site Status

Prairie Cardiovascular Consultants

Springfield, Illinois, United States

Site Status

Columbia University Medical Center

New York, New York, United States

Site Status

Wake Heart Center

Raleigh, North Carolina, United States

Site Status

Dallas VA Medical Center

Dallas, Texas, United States

Site Status

St. Joseph Hospital

Bellingham, Washington, United States

Site Status

Countries

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United States

Other Identifiers

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200-0012

Identifier Type: -

Identifier Source: org_study_id