Chronic Total Occlusion Crossing With the Wildcat Catheter

NCT ID: NCT01174784

Last Updated: 2020-07-17

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

88 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-08-31

Study Completion Date

2011-06-30

Brief Summary

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This is a prospective, multi-center, non-randomized study of the Wildcat Catheter to cross a single femoropopliteal chronic total occlusion (CTO). Safety and efficacy will be evaluated during the index procedure through 30-day follow-up.

Detailed Description

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Patients with a CTO, defined as 99% to 100% stenosis of a peripheral artery, will be approached for enrollment in the study. Following providing informed consent, the CTO will be addressed by the Wildcat catheter, which will provide a route for the advancement of guidewires and other tools beyond the CTO. Data will be collected to assess the safety efficacy of use of the device during the procedure and up to 30 days post-procedure.

Conditions

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Peripheral Arterial Disease

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Treatment

The Wildcat catheter is a CTO crossing catheter. Subjects will be subjected to crossing with this device.

Group Type EXPERIMENTAL

Chronic TOtAl OcclusioN CrossiNg with thE WildCat CatheTer

Intervention Type DEVICE

A Non-Randomized Study of the Avinger Wildcat™ used to Cross Chronic Total Occlusions in the Superficial Femoral and Popliteal Arteries

Interventions

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Chronic TOtAl OcclusioN CrossiNg with thE WildCat CatheTer

A Non-Randomized Study of the Avinger Wildcat™ used to Cross Chronic Total Occlusions in the Superficial Femoral and Popliteal Arteries

Intervention Type DEVICE

Other Intervention Names

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CONNECT

Eligibility Criteria

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Inclusion Criteria

1. Patient is willing and able to provide informed consent.
2. Patient is willing and able to comply with the study protocol.
3. Patient is \> 18 years old.
4. Patient has peripheral arterial disease requiring revascularization as evidenced by contrast, CT or MR angiography.
5. Patient has an occluded femoropopliteal artery that is 99-100% stenosed and is ≥ 1 cm and ≤ 30 cm in length by visual estimate.
6. Target femoropopliteal vessel is ≥ 3.0 mm in diameter.
7. Patient has Rutherford Classification of 2-5.

Exclusion Criteria

1. Patient has a known sensitivity or allergy to contrast materials that cannot be adequately pre-treated.
2. Patient has a known sensitivity or allergy to anti-platelet medications.
3. Patient is pregnant or lactating.
4. Patient has a co-existing disease or medical condition contraindicating percutaneous intervention.
5. Target vessel is severely calcified as evidenced by angiography.
6. Target lesion is in a bypass graft.
7. Target lesion is in a stent (i.e., in-stent restenosis).
8. Patient has had a procedure on the target limb within 7 days.
9. Patient has had a procedure on the target limb within the past 30 days and is unstable.
10. Patient is simultaneously participating in an investigational device or drug study.
11. Patient has a planned surgical or interventional procedure within 30 days after the study procedure.
Minimum Eligible Age

19 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Avinger, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Tom Davis, MD

Role: PRINCIPAL_INVESTIGATOR

St. John Hospital

Laiq Raja, MD

Role: PRINCIPAL_INVESTIGATOR

El Paso Cardiology Associates

Locations

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Birmingham Heart Clinic

Birmingham, Alabama, United States

Site Status

Arizona Regional / Adventis

Mesa, Arizona, United States

Site Status

Phoenix Heart Center

Phoenix, Arizona, United States

Site Status

Sutter Memorial

Sacramento, California, United States

Site Status

Sharp Memorial

San Diego, California, United States

Site Status

Coastal Vascular

Pensacola, Florida, United States

Site Status

Emory University Hospital

Atlanta, Georgia, United States

Site Status

Detroit Medical Center

Detroit, Michigan, United States

Site Status

St. John Hospital and Medical Center

Detroit, Michigan, United States

Site Status

Central Michigan Community Hospital

Mount Pleasant, Michigan, United States

Site Status

St. Louis University

St Louis, Missouri, United States

Site Status

Jobst Vascular Center

Toledo, Ohio, United States

Site Status

Austin Heart

Austin, Texas, United States

Site Status

Cardiology Care Consultants

El Paso, Texas, United States

Site Status

El Paso Cardiology Associates

El Paso, Texas, United States

Site Status

Countries

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United States

Other Identifiers

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AVI CTO 10001

Identifier Type: -

Identifier Source: org_study_id

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