Pathophysiologic Changes in the Respiratory System During Therapeutic Interventions

NCT ID: NCT01239433

Last Updated: 2016-09-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

25 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-05-31

Study Completion Date

2016-05-31

Brief Summary

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Airway pressures change during fiberoptic bronchoscopy and endotracheal suctioning. In this study pressure changes are examined in a mechanical lung model and in a population of ICU patients on mechanical ventilation.

Detailed Description

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Airway pressures change during fiberoptic bronchoscopy and endotracheal suctioning. In this study such pressure changes are examined in a mechanical lung model and in a population of ICU patients on mechanical ventilation. A systematic recording of airway pressures, tidal volumes and blood gases are carried out during ordinary therapeutic procedures requested by the staff physician. No additional study interventions are carried out.

The aim of the project is to examine negative effects of pressure/volume changes.

Conditions

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Respiratory Failure

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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mechanically ventilated patients

ICU patients on mechanical ventilation. Daily endotracheal suctioning performed to reduce secretions. Data recorded during these therapeutic interventions.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* \> 18 years of age
* on mechanical ventilation
* daily endotracheal suctioning performed

Exclusion Criteria

* \< 18 years of age
* non-invasive ventilation
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Oslo University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Espen Rostrup Nakstad

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Espen R Nakstad, MD

Role: PRINCIPAL_INVESTIGATOR

Oslo University Hospital - Ulleval, Norway

Helge Opdahl, MD, PhD

Role: STUDY_DIRECTOR

Ullevaal University Hospital

Locations

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Oslo University Hospital - Ulleval

Oslo, Oslo County, Norway

Site Status

Countries

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Norway

Other Identifiers

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REK S-O, Ref 2010/1340, part B

Identifier Type: -

Identifier Source: org_study_id

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