Attenuation of Pain in Men and Women

NCT ID: NCT01220414

Last Updated: 2018-02-19

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-09-30

Study Completion Date

2013-01-31

Brief Summary

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The purpose of this study is to examine opioid and endocannabinoid mechanisms of exercise-induced analgesia in men and women.

Detailed Description

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Conditions

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Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Men

Group Type ACTIVE_COMPARATOR

Naltrexone, then placebo

Intervention Type DRUG

50 mg of naltrexone

Placebo, then Naltrexone

Intervention Type DRUG

sugar pill

Women

Group Type ACTIVE_COMPARATOR

Naltrexone, then placebo

Intervention Type DRUG

50 mg of naltrexone

Placebo, then Naltrexone

Intervention Type DRUG

sugar pill

Interventions

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Naltrexone, then placebo

50 mg of naltrexone

Intervention Type DRUG

Placebo, then Naltrexone

sugar pill

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

\-

Exclusion Criteria

* current cardiac or other chronic diseases (e.g., cancer, diabetes, hypertension, kidney disease); routine use of prescriptive medications; history of vasovagal response to phlebotomy; an allergy to naltrexone; pregnancy; current smokers; current use of recreational drugs; history of substance abuse
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Wisconsin, Madison

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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University of Wisconsin-Madison

Madison, Wisconsin, United States

Site Status

Countries

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United States

Other Identifiers

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H-2010-0087

Identifier Type: -

Identifier Source: org_study_id

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