Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
500 participants
OBSERVATIONAL
2010-07-31
2011-09-30
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
A parallel goal of this study is to assess the feasibility of recruiting dentists that provide root canal therapy and patients using the DPBRN.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
DPBRN Persistent Pain and Root Canal Therapy
NCT01201668
Post Operative Sensitivity of MTA Obturation
NCT06795282
Role of PRF With MTA and Theracal After Pulpotomy in Relieving Pain
NCT03493321
Postoperative Pain After Ultrasonically and Laser-activated Irrigation During Root Canal Treatment
NCT03981237
This Prospective Study Has 2 Objectives: First, to Assess the Post-obturation Pain Utilizing Bioceramic Sealer and One Cone Technique. Second, to Compare the Intensity of Post-obturation Pain Following Unintentional Sealer Extrusion
NCT05621681
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
* Assess the frequency and intensity of pre-operative pain
* Evaluate the occurence and intensity of intra-operative pain
* Evaluate the occurence and intensity of post-operative pain
* Assess the interference of persistent tooth pain with daily life
* Identify a limited set of risk factors related to the development of post-operative pain.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
COHORT
PROSPECTIVE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Post-operativeTooth Pain
No interventions assigned to this group
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* permanent adult tooth requiring it first non-surgical root canal therapy
* patients with more than 1 tooth requiring root canal therapy are eligible, but only the first root canal procedure performed will be included to avoid problems of correlation within patients
Exclusion Criteria
* patients with obvious cognitive impairments (e.g., past stroke with communication deficits, dementia, mental disability)
* patients unable to return for 6 month follow-up, since another study plans to obtain data of these patients at that time (DPBRN Persistent Tooth Pain)
19 Years
70 Years
ALL
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
HealthPartners Institute
OTHER
Kaiser Permanente
OTHER
Permanente Dental Associates Group, Oregon
OTHER
University of Florida
OTHER
University of Copenhagen
OTHER
University of Alabama at Birmingham
OTHER
University of Minnesota
OTHER
Dental Practice-Based Research Network
NETWORK
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Gregg H. Gilbert, DDS, MBA, FAAHD
Professor and Chair, General Dental Sciences
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Donald R Nixdorf, DDS, MS
Role: PRINCIPAL_INVESTIGATOR
University of Minnesota
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
University of Alabama at Birmingham
Birmingham, Alabama, United States
University of Florida College of Dentistry
Gainesville, Florida, United States
Health Partners Dental Group
Minneapolis, Minnesota, United States
Health Partners Research Foundation
Minneapolis, Minnesota, United States
University of Minnesota
Minneapolis, Minnesota, United States
Kaiser Permanente Center for Health Research
Portland, Oregon, United States
Permanente Denrtal Associates
Portland, Oregon, United States
University of Copenhagen Royal Dental College
Copenhagen, , Denmark
Countries
Review the countries where the study has at least one active or historical site.
References
Explore related publications, articles, or registry entries linked to this study.
Nixdorf DR, Law AS, Lindquist K, Reams GJ, Cole E, Kanter K, Nguyen RHN, Harris DR; National Dental PBRN Collaborative Group. Frequency, impact, and predictors of persistent pain after root canal treatment: a national dental PBRN study. Pain. 2016 Jan;157(1):159-165. doi: 10.1097/j.pain.0000000000000343.
Law AS, Nixdorf DR, Aguirre AM, Reams GJ, Tortomasi AJ, Manne BD, Harris DR; National Dental PBRN Collaborative Group. Predicting severe pain after root canal therapy in the National Dental PBRN. J Dent Res. 2015 Mar;94(3 Suppl):37S-43S. doi: 10.1177/0022034514555144. Epub 2014 Oct 29.
Law AS, Nixdorf DR, Rabinowitz I, Reams GJ, Smith JA Jr, Torres AV, Harris DR; National Dental PBRN Collaborative Group. Root canal therapy reduces multiple dimensions of pain: a national dental practice-based research network study. J Endod. 2014 Nov;40(11):1738-45. doi: 10.1016/j.joen.2014.07.011. Epub 2014 Sep 1.
Related Links
Access external resources that provide additional context or updates about the study.
Dental Practice-Based Research Network
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
133266
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.