Hybrid Model of Vocal Inflammation and Tissue Mobilization
NCT ID: NCT01197339
Last Updated: 2016-01-25
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE1
45 participants
INTERVENTIONAL
2010-09-30
2013-03-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
FACTORIAL
BASIC_SCIENCE
SINGLE
Study Groups
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treatment
resonant voice
A 4-hr resonant voice exercise will be prescribed to subjects following vocal loading.
Breathy voice
A 4-hr breathy voice exercise will be prescribed to subjects following vocal loading.
Relaxation exercise
A 4-hr relaxation exercise will be prescribed to subjects following vocal loading.
Resonant voice and relaxation exercise
A 4-hr resonant voice and relaxation exercise will be prescribed to subjects following vocal loading.
Controls
voice rest
A 4-hr voice rest will be prescribed to subjects following vocal loading.
Interventions
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resonant voice
A 4-hr resonant voice exercise will be prescribed to subjects following vocal loading.
voice rest
A 4-hr voice rest will be prescribed to subjects following vocal loading.
Breathy voice
A 4-hr breathy voice exercise will be prescribed to subjects following vocal loading.
Relaxation exercise
A 4-hr relaxation exercise will be prescribed to subjects following vocal loading.
Resonant voice and relaxation exercise
A 4-hr resonant voice and relaxation exercise will be prescribed to subjects following vocal loading.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* ages 18-40
* generally healthy
* normal hearing bilaterally at 20 dB to 8,000 Hz
* have ability to produce "resonant voice" during training as determined by the examiner perceptually
* Tolerate rigid and nasal endoscopy without anesthesia to the larynx nasal patency allowing for the passage of an endoscope unilaterally
Exclusion Criteria
* Failing a hearing screening test
* Having current chronic voice problems
* Having current medications that are determined to possibly influence voice
* Having heightened gag reflex
* Having known or suspected allergy to anesthetics
* Pregnancy reported
18 Years
40 Years
FEMALE
Yes
Sponsors
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National Institute on Deafness and Other Communication Disorders (NIDCD)
NIH
McGill University
OTHER
Purdue University
OTHER
University of Pittsburgh
OTHER
Responsible Party
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Kittie Verdolini Abbott
Professor
Principal Investigators
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Katherine Verdolini Abbott, Ph.D.
Role: PRINCIPAL_INVESTIGATOR
University of Pittsburgh
Locations
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Univesity of Pittsburgh
Pittsburgh, Pennsylvania, United States
Countries
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References
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Li NY, Abbott KV, Rosen C, An G, Hebda PA, Vodovotz Y. Translational systems biology and voice pathophysiology. Laryngoscope. 2010 Mar;120(3):511-5. doi: 10.1002/lary.20755.
Other Identifiers
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DC008290
Identifier Type: -
Identifier Source: org_study_id
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