Efficacy of Methylsulfonylmethane Supplementation on Osteoarthritis of The Knee: A Randomized Controlled Study

NCT ID: NCT01188213

Last Updated: 2010-08-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Brief Summary

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The aim of this study was to determine the efficacy of methylsulfonylmethane (MSM) in treating patients with knee OA.

Detailed Description

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Conditions

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Knee Osteoarthritis

Study Groups

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Purified MSM

Group Type EXPERIMENTAL

Methylsulfonylmethane (MSM)

Intervention Type DIETARY_SUPPLEMENT

Interventions

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Methylsulfonylmethane (MSM)

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* symptomatic knee OA for at least 6 months according to the clinical criteria of the American College of Rheumatology (ACR)
* radiographic confirmed knee OA according to the Kellgren \& Lawrence scale

Exclusion Criteria

* acute septic arthritis
* inflammatory arthritis
* any other type of arthritis
* history of knee buckling or recent knee injury
* lack of physical or mental bility to perform or comply with the treatment procedure
* diabetes mellitus
* fibromyalgia or other chronic pain syndromes
* concurrent anti-coagulant/anti-platelet drugs
* arthroscopy or intra-articular injections in the previous 3 months
Minimum Eligible Age

40 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assaf-Harofeh Medical Center

OTHER_GOV

Sponsor Role lead

References

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Debbi EM, Agar G, Fichman G, Ziv YB, Kardosh R, Halperin N, Elbaz A, Beer Y, Debi R. Efficacy of methylsulfonylmethane supplementation on osteoarthritis of the knee: a randomized controlled study. BMC Complement Altern Med. 2011 Jun 27;11:50. doi: 10.1186/1472-6882-11-50.

Reference Type DERIVED
PMID: 21708034 (View on PubMed)

Other Identifiers

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13/05

Identifier Type: -

Identifier Source: org_study_id

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