VALIANT CAPTIVIA Post-market Registry

NCT ID: NCT01181947

Last Updated: 2023-11-08

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-02-28

Study Completion Date

2013-08-31

Brief Summary

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The Valiant Thoracic Stent Graft has been preloaded on the new Captivia Delivery System (Captivia). This new delivery system was CE marked on September 14th, 2009 and was commercially released in the European Union on October 1st, 2009.

The Valiant Thoracic Stent Graft with the Captivia Delivery System (Valiant Captivia) is designed to treat diseases of the descending thoracic aorta including but not limited to aneurysms and dissections.

The purpose of the VALIANT CAPTIVIA Registry is to collect and evaluate mid term clinical performance data of the Valiant Captivia Thoracic Stent Graft System following OUS market approval.

Detailed Description

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1. Use of controls

1. This study is a post-market registry without using a control. All analyses will be descriptive in nature and no statistical comparisons are planned.

Sample size
2. There is no sample size calculation since this is not a hypothesis driven study; VALIANT CAPTIVIA has recruited 100 subjects and will follow these subjects through for approximately 36 months.
2. Number of investigation sites and study duration

1. 15 investigation sites in Europe and Turkey where the Valiant Captivia Thoracic Stent Graft System is commercially available have enrolled 100 subjects.
2. There will be no minimum nor maximum number of enrolled subjects per investigation site.
3. The sites' compliance with the clinical investigation plan will be assessed on an ongoing basis. In case of serious non-compliance, the sponsor may decide to stop subject enrolment in a site based on the assessment.

Conditions

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Aortic Aneurysm, Thoracic

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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patients undergoing TEVAR

Those with a thoracic aortic aneurysm/dissection

TEVAR

Intervention Type DEVICE

Thoracic endovascular aneurysm repair

Interventions

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TEVAR

Thoracic endovascular aneurysm repair

Intervention Type DEVICE

Other Intervention Names

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Valiant Captivia stent graft system

Eligibility Criteria

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Inclusion Criteria

* Age ≥ 18 years or minimum age as required by local regulations
* Indication for surgical repair of thoracic aortic aneurysms and/or thoracic aortic dissections with an thoracic endovascular stent graft in accordance with the applicable guidelines on endovascular interventions and the Instructions for Use of the Valiant Captivia Thoracic Stent Graft System
* Signed consent form ('Patient informed consent form' or 'Patient Data Release Authorization Form')
* Intention to implant the Valiant Captivia Thoracic Stent Graft System or having implanted the system within the last 3 months before subject enrollment
* Willingness and ability to comply with the CIP

Exclusion Criteria

* High probability of non-adherence to physician's follow-up requirements
* Participation in concurrent interventional trial which may confound study results
* Prior implantation of a thoracic stent graft
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medtronic Cardiovascular

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Giovanni Torsello, Prof.

Role: PRINCIPAL_INVESTIGATOR

St Franziskus Hospital GmbH

Rosella Fattori, Prof.

Role: PRINCIPAL_INVESTIGATOR

Policlinico S.Orsola Malpighi

Carlos Vaquero Puerta, Dr.

Role: PRINCIPAL_INVESTIGATOR

Hospital Clínico Universitario de Valladolid

Matthew Thompson, Prof.

Role: PRINCIPAL_INVESTIGATOR

St. George's Hospital

Werner Jaschke, Prof.

Role: PRINCIPAL_INVESTIGATOR

Medical University of Innsbruck

Yigit Goktay, Prof.

Role: PRINCIPAL_INVESTIGATOR

Dokuz Eylul University

Karl Heinz Orend, Prof.

Role: PRINCIPAL_INVESTIGATOR

Universitatsklinikum Ulm

Omke Teebken, Prof.

Role: PRINCIPAL_INVESTIGATOR

Hannover Medical School

Thomas Schmitz-Rixen, Prof.

Role: PRINCIPAL_INVESTIGATOR

Klinikum der J.W.Goethe-Universitat

Markus Steinbauer, Dr.

Role: PRINCIPAL_INVESTIGATOR

Krankenhaus Barmherzige Bruder Regensburg

Stephan Zangos, Dr.

Role: PRINCIPAL_INVESTIGATOR

Klinikum der Johann-Wolfgang-Goethe - Institut fur Diagnostische und Interventionelle Radiologie

Joep Teijink, Dr.

Role: PRINCIPAL_INVESTIGATOR

Catharina Ziekenhuis

Robin Heijmen, Dr.

Role: PRINCIPAL_INVESTIGATOR

St. Antonius Hospital

Mustafa Parildar, Prof.

Role: PRINCIPAL_INVESTIGATOR

Ege University Hospital

Fatih Boyvat, Prof.

Role: PRINCIPAL_INVESTIGATOR

Baskent University Ankara Hospital

Locations

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Medical University of Innsbruck

Innsbruck, , Austria

Site Status

Klinikum der J.W.Goethe-Universitat

Frankfurt am Main, , Germany

Site Status

Klinikum der Johann-Wolfgang-Goethe - Institut fur Diagnostische und Interventionelle Radiologie

Frankfurt am Main, , Germany

Site Status

Medizinische Hochschule Hannover

Hanover, , Germany

Site Status

St Franziskus Hospital GmbH

Münster, , Germany

Site Status

Krankenhaus Barmherzige Bruder Regensburg

Regensburg, , Germany

Site Status

Universitatsklinikum Ulm

Ulm, , Germany

Site Status

Polyclinic Hospital S.Orsola - Malpighi

Bologna, , Italy

Site Status

Catharina Ziekenhuis

Eindhoven, , Netherlands

Site Status

St. Antonius Ziekenhuis

Nieuwegein, , Netherlands

Site Status

Hospital Clinico Universitario de Valladolid

Valladolid, , Spain

Site Status

Baskent University Ankara Hospital

Ankara, , Turkey (Türkiye)

Site Status

Dokuz Eylul University

Izmir, , Turkey (Türkiye)

Site Status

Ege University Hospital

Izmir, , Turkey (Türkiye)

Site Status

St George's Hospital

London, , United Kingdom

Site Status

Countries

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Austria Germany Italy Netherlands Spain Turkey (Türkiye) United Kingdom

References

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Heijmen RH, Thompson MM, Fattori R, Goktay Y, Teebken OE, Orend KH. Valiant thoracic stent-graft deployed with the new captivia delivery system: procedural and 30-day results of the Valiant Captivia registry. J Endovasc Ther. 2012 Apr;19(2):213-25. doi: 10.1583/11-3652MR.1.

Reference Type DERIVED
PMID: 22545887 (View on PubMed)

Other Identifiers

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MDTEV20112009

Identifier Type: -

Identifier Source: org_study_id

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