Sonographic Differences in Brain Measurements Between Normal and Intrauterine Growth Restriction (IUGR) Fetuses

NCT ID: NCT01178619

Last Updated: 2013-08-28

Basic Information

• Recruitment Status: WITHDRAWN
• Study Classification: OBSERVATIONAL
• Study Start Date: 2010-09-30
• Study Completion Date: 2012-08-31

Brief Summary

Intrauterine growth restriction is being suspected in cases where the fetal estimated weight is less then the 10 th percentile for its gestational age. Abdominal circumference is the most influenced measurement in this cases. Head circumference on the other hand can be or not be influenced. Previous studies have shown that transverse cerebellar diameter (TCD) is constant to gestational age and is not influenced by IUGR.Other showed lower TCD in IUGR fetuses. We would like to study the differences in cerebellar, vermian and corpus callosum growth between normal to IUGR fetuses and between symmetrical and asymmetrical IUGR. In this observational study we will include pregnant women between 28-37 gestational week with a singleton otherwise normal pregnancies. We will measure the fetal TCD, vermian distances and the CC, abdominal circumference, head circumference and femur length. we will compeer these measurements according to the following groups:normal fetuses, symmetrical and asymmetrical IUGR.

Conditions

Intra-uterine Growth Restriction

Study Design

• Observational Model Type: CASE_CONTROL

Study Groups

AGA

No interventions assigned to this group

symmetrical IUGR

No interventions assigned to this group

asymmetrical IUGR

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• singleton,
• 28-37 GA,
• well dated pregnancy.

Exclusion Criteria

• multifetal pregnancies,
• no first trimester dating,
• fetuses with known chromosomal or structural anomalies.

• Minimum Eligible Age: 28 Weeks
• Maximum Eligible Age: 37 Weeks
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Meir Medical Center

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Other Identifiers

MMC10095-2010CTIL

Identifier Type: -

Identifier Source: org_study_id