Evaluating The Safety Of Exemestane Following 2-3 Years Of Adjuvant Tamoxifen Therapy In Postmenopausal Early Breast Cancer Patients

NCT ID: NCT01155063

Last Updated: 2012-10-01

Study Results

Results available

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Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

89 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-09-30

Study Completion Date

2011-09-30

Brief Summary

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Evaluating the safety, tolerability and efficacy of Aromasin® when used in routine clinical practice, evaluating adherence to prescribed Aromasin® treatment and to understand reasons for early discontinuation.

Detailed Description

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This study was terminated on 01-Aug-2011 due to very low potential to enroll planned number of patients or any sufficient number of patients for complete statistical analyses. This study is not being terminated because of safety or efficacy concerns.

Conditions

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Early Breast Cancer

Keywords

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Exemestane Adjuvant Treatment In Postmenopausal Women Estrogen Receptor Positive Early Breast Cancer Tamoxifen

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Main Group

Postmenopausal Women With Invasive, Estrogen Receptor Positive Early Breast Cancer Who Are Disease-Free After 2-3 Years Of Initial Adjuvant Tamoxifen Therapy

Aromasin (exemestane)

Intervention Type OTHER

Aromasin (exemestane), tablets 25 mg, once a day

Interventions

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Aromasin (exemestane)

Aromasin (exemestane), tablets 25 mg, once a day

Intervention Type OTHER

Other Intervention Names

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Aromasin, exemestane

Eligibility Criteria

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Inclusion Criteria

* Postmenopausal females.
* Patients who have had surgical treatment for histological confirmed breast cancer that was non-metastatic at the time of the initial diagnosis.
* Patients who are disease-free after 2 or 3 years of adjuvant tamoxifen treatment.
* Patients whose tumour was estrogen receptor positive (ER+).
* Evidence of a personally signed and dated informed consent document indicating that the subject (or a legally acceptable representative) has been informed of all pertinent aspects of the study.

Exclusion Criteria

* Patients for whom Aromasin® treatment is contraindicated (see SPC).
* Presence of metastasis or a contra lateral tumour.
* Other adjuvant endocrine therapy.
* Another concomitant antineoplastic treatment.
* Participation in a clinical trial with an investigational drug during the 30 days prior to enrolment in the study.
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Pfizer

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Pfizer CT.gov Call Center

Role: STUDY_DIRECTOR

Pfizer

Related Links

Other Identifiers

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A5991092

Identifier Type: -

Identifier Source: org_study_id