Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE1
21 participants
INTERVENTIONAL
2010-06-30
2017-01-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
OTHER
SINGLE
Study Groups
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Trimethaphan
Response to intrabrachial vasodilators during autonomic withdrawal
Trimethaphan
Trimethaphan 4 mg/min IV, for the duration of the study (approximately 2 hours)
Placebo
Response to intrabrachial vasodilators during saline intravenous (IV) infusion
Placebo
Response to intrabrachial vasodilators during IV saline infusion
Interventions
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Trimethaphan
Trimethaphan 4 mg/min IV, for the duration of the study (approximately 2 hours)
Placebo
Response to intrabrachial vasodilators during IV saline infusion
Other Intervention Names
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Eligibility Criteria
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Exclusion Criteria
* Subjects unable to give voluntary informed consent
* Subjects on anticoagulant drugs or anemic
* Subjects with a recent medical illness
* Subjects with a history of coronary heart disease
* Subjects with known kidney or liver disease
* Subjects with recent weight loss or consuming low carbohydrate diet
18 Years
60 Years
ALL
Yes
Sponsors
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Vanderbilt University
OTHER
Responsible Party
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Alfredo Gamboa
Research Assistant Professor
Locations
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Vanderbilt University Medical Center
Nashville, Tennessee, United States
Countries
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Other Identifiers
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091489
Identifier Type: -
Identifier Source: org_study_id
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