Evaluation of a Test Mouthwash and Dentifrice Regimen in an In-situ Model of Dental Erosion
NCT ID: NCT01128972
Last Updated: 2015-01-01
Study Results
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View full resultsBasic Information
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COMPLETED
PHASE2
36 participants
INTERVENTIONAL
2009-08-31
2009-10-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
TREATMENT
SINGLE
Study Groups
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Test Dentifrice + Test Mouth Rinse (MR)
Test fluoride dentifrice and test fluoride MR
Sodium fluoride
Test fluoride toothpaste and test fluoride mouth rinse
Test Dentifrice + Sterile Water Rinse
Test fluoride dentifrice and sterile water rinse
Sodium fluoride
Test fluoride toothpaste and test fluoride mouth rinse
Sterile water
Sterile water rinse
Placebo Dentifrice + Test MR
Placebo dentifrice and test fluoride rinse
Sodium fluoride
Test fluoride toothpaste and test fluoride mouth rinse
Reference Dentifrice + Sterile Water Rinse
Marketed fluoride dentifrice with sterile water rinse
Sodium fluoride
Test fluoride toothpaste and test fluoride mouth rinse
Sodium monoflurophosphate
United Kingdom marketed fluoride toothpaste
Sterile water
Sterile water rinse
Placebo Dentifrice + Sterile Water Rinse
Placebo dentifrice and sterile water rinse
Sterile water
Sterile water rinse
Interventions
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Sodium fluoride
Test fluoride toothpaste and test fluoride mouth rinse
Sodium monoflurophosphate
United Kingdom marketed fluoride toothpaste
Sterile water
Sterile water rinse
Eligibility Criteria
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Inclusion Criteria
* No current active caries or periodontal disease that may compromise the study or the health of the subjects
* A gum base stimulated whole saliva flow rate greater than or equal to 0.8 mL/minute and an unstimulated whole saliva flow rate greater than or equal to 0.2 mL/minute
Exclusion Criteria
18 Years
65 Years
ALL
Yes
Sponsors
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GlaxoSmithKline
INDUSTRY
Responsible Party
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Principal Investigators
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GSK Clinical Trials
Role: STUDY_DIRECTOR
GlaxoSmithKline
Locations
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Indiana University School of Dentistry
Indianapolis, Indiana, United States
Countries
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References
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Maggio B, Guibert RG, Mason SC, Karwal R, Rees GD, Kelly S, Zero DT. Evaluation of mouthrinse and dentifrice regimens in an in situ erosion remineralisation model. J Dent. 2010 Nov;38 Suppl 3:S37-44. doi: 10.1016/S0300-5712(11)70007-0.
Other Identifiers
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Z3480664
Identifier Type: -
Identifier Source: org_study_id
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