Computer-based Cognitive Training for Parkinson Disease

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-07-31

Study Completion Date

2012-04-30

Brief Summary

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Parkinson's Disease (PD) is a neurodegenerative, progressive illness. It is a multi-system disease that influences not only the motor but also the cognitive and autonomic systems. The main cognitive impairment in individuals with PD is found in executive function (EF). EF is defined as a set of cognitive skills necessary for planning, monitoring and executing sequences of complex activities.

The primary study hypothesis is that computer-based training aimed at improving executive function will have a beneficial effect on gait functions.

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Detailed Description

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Parkinson Disease (PD) is a neurodegenerative, progressive illness. It is a multi-system disease that influences not only the motor but also the cognitive and autonomic systems. The main cognitive impairment in individuals with PD is found in executive function (EF). EF is defined as a set of cognitive skills necessary for planning, monitoring and executing sequences of complex activities. Previous studies have revealed some relation between cognitive states and physical functions in healthy adults. Few studies have examined the effect of computer-based cognitive training on various populations. These studies showed a positive emotional-cognitive effect in those populations. This type of intervention plan was also applied to PD patients. However, there are no reports on the effect of intentional cognitive training on gait functions. The purpose of the study is to assess whether cognitive training, designed to improve EF ability, can also improve gait function in PD patients.

Conditions

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Parkinson Disease Gait

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Computerized cognitive training

A 12 week computerized cognitive training

Group Type EXPERIMENTAL

Computerized cognitive training

Intervention Type OTHER

A 12 week computerized cognitive training at home with the Attengo™ software program.

Interventions

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Computerized cognitive training

A 12 week computerized cognitive training at home with the Attengo™ software program.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. Idiopathic PD.
2. Aged 50-80, living in north region of Israel.
3. Receive regular medications for PD.
4. Not suffering from irregular cognitive disturbance or MMSE\<25.
5. Measured 1-3 on the Hoehn \& Yahr scale.
6. Have access to a computer and the ability to operate it.

Exclusion Criteria

1. Brain operation, including DBS transplant.
2. History of orthopedic problems that can impair gait (hip/knee fractures and back problems).
3. Orthopedic operation on lower limbs performed no later than six months prior to the beginning of the study.
4. Unbalanced general health: uncontrolled diabetes or blood pressure, etc.
5. Inability to walk independently.
6. Immunodeficiency diseases, active cancer, ischemic diseases.
7. Vision impairment, partial/full blindness.
8. Having participated in similar research or cognitive assessment during the previous year.
9. Have received cognitive or gait training under physical therapy or other programs.

Minimum Eligible Age

50 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Uzi Milman

Director, Clinical Research Unit, Clalit Health Services, Haifa and Western Galilee District and the Department of Family Medicine, Faculty of Medicine, Technion- Israel Institute of Technology, HAIFA, ISRAEL.

Responsibility Role PRINCIPAL_INVESTIGATOR