A Retrospective Study of Cardiovascular Events Related to the Use of Glucose Lowering Drug Treatment in Primary Care

NCT ID: NCT01121315

Last Updated: 2012-05-11

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 58326 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2010-05-31
• Study Completion Date: 2011-08-31

Brief Summary

To describe the type II diabetes population in primary care with special reference to treatment, other diseases and mortality during the last decade. To test the hypothesis that the type or combination of per oral glucose lowering drugs have different effects on the risk of cardiovascular disease and diabetic complications.

Conditions

Diabetes Type II

Study Design

• Study Time Perspective: RETROSPECTIVE

Study Groups

1

Diabetes type II patients, according to medical records, prescriptions or lab results, followed for \>6 months after diagnosis.

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• Patients with type II diabetes, according to medical records, diagnosis, prescription or lab assessments

Exclusion Criteria

• Patients followed by physician for less than 6 months after diagnosis of Diabetes type II

• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

AstraZeneca

INDUSTRY

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Leif Lohm, MD

Role: STUDY_DIRECTOR

AstraZeneca Nordic, Södertälje

Gunnar Johansson, MD

Role: PRINCIPAL_INVESTIGATOR

Uppsala University, Sweden

Carl Johan Östgren, MD

Role: STUDY_CHAIR

Ödeshögs VC

Johan Sundström, MD PhD

Role: STUDY_CHAIR

Uppsala University Hospital

Locations

Research Site

Uppsala, , Sweden

Countries

Sweden

References

Grundvold I, Bodegard J, Nilsson PM, Svennblad B, Johansson G, Ostgren CJ, Sundstrom J. Body weight and risk of atrial fibrillation in 7,169 patients with newly diagnosed type 2 diabetes; an observational study. Cardiovasc Diabetol. 2015 Jan 15;14:5. doi: 10.1186/s12933-014-0170-3.

Reference Type: DERIVED

PMID: 25589001 (View on PubMed)

Sundstrom J, Sheikhi R, Ostgren CJ, Svennblad B, Bodegard J, Nilsson PM, Johansson G. Blood pressure levels and risk of cardiovascular events and mortality in type-2 diabetes: cohort study of 34 009 primary care patients. J Hypertens. 2013 Aug;31(8):1603-10. doi: 10.1097/HJH.0b013e32836123aa.

Reference Type: DERIVED

PMID: 23625112 (View on PubMed)

Ostgren CJ, Sundstrom J, Svennblad B, Lohm L, Nilsson PM, Johansson G. Associations of HbA1c and educational level with risk of cardiovascular events in 32,871 drug-treated patients with Type 2 diabetes: a cohort study in primary care. Diabet Med. 2013 May;30(5):e170-7. doi: 10.1111/dme.12145. Epub 2013 Mar 13.

Reference Type: DERIVED

PMID: 23350893 (View on PubMed)

Other Identifiers

NIS-CSE-DUM-2010/1

Identifier Type: -

Identifier Source: org_study_id