To Evaluate the Effect of Gemfibrozil on the Pharmacokinetics and Pharmacodynamics of a Single Dose of AZD1656
NCT ID: NCT01083212
Last Updated: 2010-07-01
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE1
19 participants
INTERVENTIONAL
2010-03-31
2010-06-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
TREATMENT
NONE
Study Groups
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1
Gemfibrozil day 1-5 + AZD1656 day 4, 1 week without, Placebo day 1-5 + AZD1656 day 4
AZD1656
Single dose,oral tablet
Gemfibrozil
Oral tablet bid on day 1 - 5.
Placebo
Oral tablet bid on day 1-5
2
Placebo day 1-5 + AZD1656 day 4, 1 week without, Gemfibrozil day 1-5 + AZD1656 day 4
AZD1656
Single dose,oral tablet
Gemfibrozil
Oral tablet bid on day 1 - 5.
Placebo
Oral tablet bid on day 1-5
Interventions
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AZD1656
Single dose,oral tablet
Gemfibrozil
Oral tablet bid on day 1 - 5.
Placebo
Oral tablet bid on day 1-5
Eligibility Criteria
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Inclusion Criteria
* Body mass index between ≥19 and ≤42 kg/m2.
Exclusion Criteria
* Clinically significant illness or clinically relevant trauma.
18 Years
75 Years
ALL
No
Sponsors
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AstraZeneca
INDUSTRY
Responsible Party
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AstraZeneca
Principal Investigators
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Stanko Skrtic
Role: STUDY_DIRECTOR
AstraZeneca
Aslak Rautio
Role: PRINCIPAL_INVESTIGATOR
Quintiles Hermelinen AB
Wolfgang Kuhn
Role: PRINCIPAL_INVESTIGATOR
Quintiles AB
Folke Sjöberg
Role: PRINCIPAL_INVESTIGATOR
J.J. Berzelius Clinical Research Center AB
Mirjana Kujacic
Role: STUDY_CHAIR
AstraZeneca
Locations
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Reserach Site
Linköping, , Sweden
Research Site
Luleå, , Sweden
Research Site
Uppsala, , Sweden
Countries
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Other Identifiers
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D1020C00030
Identifier Type: -
Identifier Source: org_study_id
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