Blood Volume and Fluid Kinetics in Patients Undergoing Extracorporal Circulation
NCT ID: NCT01115166
Last Updated: 2012-10-08
Study Results
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View full resultsBasic Information
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COMPLETED
10 participants
OBSERVATIONAL
2010-05-31
2012-05-31
Brief Summary
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Detailed Description
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Hemoglobin is measured every 5 minutes during one hour beginning shortly before start of the heart-lung machine. When the extracorporal circulation begins the hemoglobin decreases due to the quick mix and dilution of the priming fluid from the heart-lung machine with the patients blood.
From the amount of priming fluid and the fall of the hemoglobin, the blood volume can be calculated. If no further fluid is given the next 20 to 30 minutes, the hemoglobin concentration will in most cases increase as a result of the fluid loss from the vascular space. This increase in combination with the diureses can be used to calculate the intravascular fluid loss to the interstitium during surgery.
Sodium concentration will also be measured in parallel with the hemoglobin concentration.
The Sodium concentrations in combination with given and excreted (urine)Sodium can be used in a mass balance to calculate if intracellular edema is induced.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Cardiac surgery
Patients subjected to open cardiac surgery with the help of extracorporal circulation.
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* consent to participation
18 Years
90 Years
ALL
No
Sponsors
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University Hospital, Linkoeping
OTHER
Responsible Party
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Joachim Zdolsek
MD, PhD
Principal Investigators
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Joachim Zdolsek, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
University Hospital, Linköping, Sweden
Locations
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University Hospital, Thoracic operation ward
Linköping, Linkoeping, Sweden
Countries
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References
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Tornudd M, Hahn RG, Zdolsek JH. Fluid distribution kinetics during cardiopulmonary bypass. Clinics (Sao Paulo). 2014 Aug;69(8):535-41. doi: 10.6061/clinics/2014(08)06.
Other Identifiers
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BVECC
Identifier Type: -
Identifier Source: org_study_id
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