The Efficacy and Cost Effectiveness of Preoperative and Postoperative Cryotherapy in Proximal Tibia Fractures

NCT ID: NCT01104831

Last Updated: 2017-05-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

PHASE3

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-04-30

Study Completion Date

2012-11-30

Brief Summary

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Consenting patients with proximal tibia fractures will be randomized to 10 degree or 21 degree cryotherapy sleeves. Time to discharge and complications will be monitored.

Primary outcome measure: Cost of Treatment (based on length of stay) Secondary outcome measures: Satisfaction/pain relief and narcotic requirement

Detailed Description

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Conditions

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Proximal Tibia Fracture

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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21 degree Cooling

Room temperature water circulated through cryotherapy sleeve.

Group Type PLACEBO_COMPARATOR

Room temperature cuff

Intervention Type DEVICE

sleeve with room temperature water placed over fracture site.

10 degree cooling

Cooled water circulated through a cryotherapy sleeve.

Group Type ACTIVE_COMPARATOR

Cryotherapy

Intervention Type DEVICE

cooled sleeve placed over fracture site.

Interventions

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Cryotherapy

cooled sleeve placed over fracture site.

Intervention Type DEVICE

Room temperature cuff

sleeve with room temperature water placed over fracture site.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Skeletally mature
* Trauma patients with single-system musculoskeletal injuries.
* Proximal tibia fractures treated with open reduction and internal fixation.
* Unilateral proximal tibial injuries.

Exclusion Criteria

* Previous ipsilateral knee surgery
* Upper extremity injuries impairing mobilization
* Pre-existing ipsilateral neurologic condition or acute ipsilateral neurologic injury
* Associated injuries impairing mobilization
* Suspected or confirmed compartment syndrome
* Open fractures
* Patients previously on narcotics
* Patients with impaired sensorium Concurrent head injury Intoxication
Minimum Eligible Age

17 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Orthopedic Research and Education Foundation

OTHER

Sponsor Role collaborator

Orthopedic Trauma Association

UNKNOWN

Sponsor Role collaborator

University of Manitoba

OTHER

Sponsor Role lead

Responsible Party

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University of Manitoba

Principal Investigators

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Jesse A Shantz, MD, MBA

Role: PRINCIPAL_INVESTIGATOR

University of Manitoba

Locations

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Winnipeg Health Sciences Centre

Winnipeg, Manitoba, Canada

Site Status

Countries

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Canada

Other Identifiers

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B2009:035

Identifier Type: -

Identifier Source: org_study_id

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