Partial Wave Spectroscopic Detection of Colon Cancer Risk

NCT ID: NCT01095432

Last Updated: 2016-05-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-03-31

Study Completion Date

2015-11-30

Brief Summary

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The purpose of this study is to study samples of rectal mucosa (the moist lining of the rectum) using a new light scattering technology, called partial wave spectroscopy (PWS) in patients who will undergo a standard of care colonoscopy or a flexible sigmoidoscopy and have a history of ulcerative colitis (UC).

Detailed Description

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The purpose of this study is to study samples of rectal mucosa (the moist lining of the rectum) using a new light scattering technology, called partial wave spectroscopy (PWS)in patients who will undergo a colonoscopy or a flexible sigmoidoscopy and have a history of ulcerative colitis (UC). PWS has been recently developed to allow scientists to learn about any changes to the cells that may indicate a risk of developing colon cancer. We believe that the PWS test will more accurately detect the risk of colon cancer.

Conditions

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Ulcerative Colitis Colon Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Main Study Group

All subjects who are undergoing a standard of care colonoscopy for flexible sigmoidoscopy and have a history of UC and agree to participate will be in the main study group.

PWS Testing

Intervention Type PROCEDURE

Partial wave spectroscopy (PWS)has been developed to allow scientists to learn about any changes to the cells that may indicate a risk of developing colon cancer.

Interventions

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PWS Testing

Partial wave spectroscopy (PWS)has been developed to allow scientists to learn about any changes to the cells that may indicate a risk of developing colon cancer.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patient must be 18 years old or older.
* Patient is already scheduled for a standard of care colonoscopy or flexible sigmoidoscopy.
* Patient has not received chemotherapy.
* History of ulcerative colitis.

Exclusion Criteria

* Patient is unable to give informed consent..
* Patient has received chemo or radiation therapy within the past 3 months.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Northwestern University

OTHER

Sponsor Role collaborator

University of Chicago

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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David T Rubin, MD

Role: PRINCIPAL_INVESTIGATOR

University of Chicago

Locations

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University of Chicago, DCAM

Chicago, Illinois, United States

Site Status

Countries

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United States

Other Identifiers

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10-066-B

Identifier Type: -

Identifier Source: org_study_id

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