Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
7243 participants
INTERVENTIONAL
2010-07-31
2013-08-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Thrombus aspiration
Thrombus aspiration is then followed by standard balloon angioplasty (PCI).
Thrombus aspiration
Aspiration of thrombus material before angioplasty
Standard balloon angioplasty (PCI)
Thrombus aspiration
Aspiration of thrombus material before angioplasty
Interventions
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Thrombus aspiration
Aspiration of thrombus material before angioplasty
Eligibility Criteria
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Inclusion Criteria
* Correspondence between ECG findings and culprit artery pathoanatomy
* A minimum of 50% stenosis in culprit artery by visual estimate
* Possibility to perform thrombus aspiration
Exclusion Criteria
* Inability to provide informed consent
* Age below 18 years
* Previous randomization in the TASTE trial
18 Years
ALL
No
Sponsors
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Uppsala University
OTHER
Region Örebro County
OTHER
Responsible Party
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Ole Frobert, MD, PhD
MD, PhD
Principal Investigators
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Ole Fröbert, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
Region Örebro County
Locations
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Skejby Hospital, Aarhus University Hospital
Aarhus, , Denmark
Landspitali University Hospital
Reykjavik, , Iceland
Södra Älvsborgs sjukhus
Borås, , Sweden
Mälarsjukhuset
Eskilstuna, , Sweden
Falu lasarett
Falun, , Sweden
Gävle sjukhus
Gävle, , Sweden
Sahlgrenska sjukhuset
Gothenburg, , Sweden
Östra sjukhuset
Gothenburg, , Sweden
Hallands sjukhus
Halmstad, , Sweden
Helsingborgs lasarett
Helsingborg, , Sweden
Länssjukhuset Ryhov
Jönköping, , Sweden
Länssjukhuset
Kalmar, , Sweden
Blekingesjukhuset
Karlskrona, , Sweden
Svensk PCI AB, Centralsjukhuset
Karlstad, , Sweden
Centralsjukhuset
Kristianstad, , Sweden
Universitetssjukhuset
Linköping, , Sweden
Sunderby sjukhus
Luleå, , Sweden
Lund University Hospital
Lund, , Sweden
Skånes universitetssjukhus
Malmo, , Sweden
Örebro University Hospital
Örebro, , Sweden
Karolinska universitetssjukhuset
Solna, , Sweden
Danderyds sjukhus
Stockholm, , Sweden
S:t Görans sjukhus
Stockholm, , Sweden
Södersjukhuset
Stockholm, , Sweden
Länssjukhuset
Sundsvall, , Sweden
Norra Älvsborgs länssjukhus
Trollhättan, , Sweden
Universitetssjukhuset
Umeå, , Sweden
Uppsala University Hospital
Uppsala, , Sweden
Centrallasarettet
Västerås, , Sweden
Countries
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References
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Calais F, Lagerqvist B, Leppert J, James SK, Frobert O. Thrombus aspiration in patients with large anterior myocardial infarction: A Thrombus Aspiration in ST-Elevation myocardial infarction in Scandinavia trial substudy. Am Heart J. 2016 Feb;172:129-34. doi: 10.1016/j.ahj.2015.11.012. Epub 2015 Nov 22.
Frobert O, Calais F, James SK, Lagerqvist B. ST-elevation myocardial infarction, thrombus aspiration, and different invasive strategies. A TASTE trial substudy. J Am Heart Assoc. 2015 Jun 15;4(6):e001755. doi: 10.1161/JAHA.114.001755.
Lagerqvist B, Frobert O, Olivecrona GK, Gudnason T, Maeng M, Alstrom P, Andersson J, Calais F, Carlsson J, Collste O, Gotberg M, Hardhammar P, Ioanes D, Kallryd A, Linder R, Lundin A, Odenstedt J, Omerovic E, Puskar V, Todt T, Zelleroth E, Ostlund O, James SK. Outcomes 1 year after thrombus aspiration for myocardial infarction. N Engl J Med. 2014 Sep 18;371(12):1111-20. doi: 10.1056/NEJMoa1405707. Epub 2014 Sep 1.
Frobert O, Lagerqvist B, Olivecrona GK, Omerovic E, Gudnason T, Maeng M, Aasa M, Angeras O, Calais F, Danielewicz M, Erlinge D, Hellsten L, Jensen U, Johansson AC, Karegren A, Nilsson J, Robertson L, Sandhall L, Sjogren I, Ostlund O, Harnek J, James SK; TASTE Trial. Thrombus aspiration during ST-segment elevation myocardial infarction. N Engl J Med. 2013 Oct 24;369(17):1587-97. doi: 10.1056/NEJMoa1308789. Epub 2013 Aug 31.
Frobert O, Lagerqvist B, Gudnason T, Thuesen L, Svensson R, Olivecrona GK, James SK. Thrombus Aspiration in ST-Elevation myocardial infarction in Scandinavia (TASTE trial). A multicenter, prospective, randomized, controlled clinical registry trial based on the Swedish angiography and angioplasty registry (SCAAR) platform. Study design and rationale. Am Heart J. 2010 Dec;160(6):1042-8. doi: 10.1016/j.ahj.2010.08.040.
Frobert O, Lagerqvist B, Kreutzer M, Olivecrona GK, James SK. Thrombus aspiration in ST-elevation myocardial infarction in Sweden: a short report on real world outcome. Int J Cardiol. 2010 Dec 3;145(3):572-3. doi: 10.1016/j.ijcard.2010.05.044. Epub 2010 Jun 13. No abstract available.
Related Links
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Related Info
Other Identifiers
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SCAAR-001
Identifier Type: -
Identifier Source: org_study_id
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