Intraperitoneal Techniques of Local Anaesthesia During Laparoscopic Cholecystectomy
NCT ID: NCT01090882
Last Updated: 2024-06-20
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
NA
128 participants
INTERVENTIONAL
2009-07-31
2009-10-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Methods Double blind randomised controlled trial of 128 consecutive subjects undergoing elective LC. Control -sham injection of diaphragm and sham wash over liver/GB with saline; Test treatment 'subperitoneal LA' - bupivocaine injection/sham wash; Internal control 'topical LA' - sham injection/bupivocaine wash. Primary outcome: pain scores in theatre recovery and the ward. Secondary outcomes: analgesic use, physiological observations, time to eating and mobilising, day case surgery.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Randomized Control Trial of Intraperitoneal Bupivacaine During Cholecystectomy
NCT01528722
Laparoscopic-Assisted Transversus Abdominus Plane Block Versus Intraperitoneal Irrigation of Local Anesthetic for Patients Undergoing Laparoscopic Cholecystectomy
NCT06714279
Local Infiltration With Levobupivacaine During Laparoscopic Cholecystectomy
NCT04697329
Intraperitoneal Analgesia After Laparoscopic Cholecystectomy
NCT00950625
The Effect of Intravenous Lidocaine and Intraperitoneal Lidocaine Irrigation on Pain After Laparoscopic Cholecystectomy
NCT01608373
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
FACTORIAL
TREATMENT
QUADRUPLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Control
Sham wash, sham injection
0.9% normal saline solution
20ml 0.9% NaCl
Subperitoneal injection
Local anaesthetic injection to diaphragm with sham wash over liver and gall bladder
Bupivocaine
20ml 0.25% at beginning of operation
Topical LA
Local anaesthetic washed over gall bladder and liver. Sham injection of diaphragm
Bupivocaine
20ml 0.25% at beginning of operation
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Bupivocaine
20ml 0.25% at beginning of operation
0.9% normal saline solution
20ml 0.9% NaCl
Other Intervention Names
Discover alternative or legacy names that may be used to describe the listed interventions across different sources.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* 18 years old or over
Exclusion Criteria
* Under 18 year olds
18 Years
ALL
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
University Hospitals Coventry and Warwickshire NHS Trust
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Keith J Roberts, MRCS
Role: PRINCIPAL_INVESTIGATOR
University Hospital Coventry and Warwickshire NHS Trust
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
UHCW NHS Trust
Coventry, Warwickshire, United Kingdom
Countries
Review the countries where the study has at least one active or historical site.
References
Explore related publications, articles, or registry entries linked to this study.
Roberts KJ, Gilmour J, Pande R, Nightingale P, Tan LC, Khan S. Efficacy of intraperitoneal local anaesthetic techniques during laparoscopic cholecystectomy. Surg Endosc. 2011 Nov;25(11):3698-705. doi: 10.1007/s00464-011-1757-3. Epub 2011 Jun 3.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
UHCW 1
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.