Cardiovascular Evaluation Before Renal Transplantation

NCT ID: NCT01064674

Last Updated: 2010-02-08

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 100 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2009-12-31
• Study Completion Date: 2010-09-30

Brief Summary

Due to rising importance of cardiovascular disease before and after renal transplantation we have changed our standard diagnostic procedure and perform stress echocardiography and myocardial scintigraphy. We would like to monitor these results and the outcome of our patients.

Detailed Description

Chronic kidney disease is a well-known risk factor for cardiovascular disease. Patients waiting for a renal transplantation usually undergo an extensive diagnostic procedure to avoid complications after transplantation such as neoplasia or inflammation. In the past years, cardiovascular complications before and after renal transplantation have gained more attention. We therefore have changed our standard diagnostic procedure before renal transplantation and perform stress echocardiography and myocardial scintigraphy. Thus we would like to evaluate our new standard diagnostic procedure and observe the results of these diagnostic procedures as well as their impact on clinical outcome.

Conditions

Chronic Kidney Disease; Coronary Artery Disease

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

before renal transplantation

Patients with CKD IV° to V° who are actually registering for a renal transplantation in our department.

diagnostic procedure

Intervention Type: OTHER

Cardiovascular diagnostic standard procedure before renal transplantation using stress echocardiography and stress myocardial scintigraphy.

Interventions

diagnostic procedure

Cardiovascular diagnostic standard procedure before renal transplantation using stress echocardiography and stress myocardial scintigraphy.

Intervention Type: OTHER

Other Intervention Names

diagnostic standard procedure

Eligibility Criteria

Inclusion Criteria

• endstage renal disease
• preparing for renal transplantation

Exclusion Criteria

• children (< 18 years)
• women who are pregnant or nursing
• patients who are also awaiting heart transplantation or have already a heart transplant
• severe mental illness

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

University Hospital Muenster

OTHER

Sponsor Role: lead

Responsible Party

Internal Medicine D, University Hospital of Muenster

Principal Investigators

Barbara Suwelack, MD

Role: PRINCIPAL_INVESTIGATOR

University Hospital Muenster

Hermann Pavenstädt, MD

Role: STUDY_CHAIR

University Hospital Muenster

Holger Reinecke, MD

Role: STUDY_CHAIR

University Hospital Muenster

Otmar Schober, MD, PhD

Role: STUDY_CHAIR

University Hospital Muenster

Locations

Department of Internal Medicine D, University Hospital Muenster

Münster, , Germany

Site Status: RECRUITING

Countries

Germany

Central Contacts

Barbara Suwelack, MD

Role: CONTACT

barbara.suwelack@ukmuenster.de

00492518347540

Viola Malyar, MD

Role: CONTACT

viola.malyar@ukmuenster.de

00492518347540

Facility Contacts

Barbara Suwelack, MD

Role: primary

barbara.suwelack@ukmuenster.de

00492518347540

Viola Malyar, MD

Role: backup

viola.malyar@ukmuenster.de

00492518347540

Other Identifiers

HerzundNierenMünster

Identifier Type: REGISTRY

Identifier Source: secondary_id

KVDiagnostikpratransplantation

Identifier Type: -

Identifier Source: org_study_id