Home
Clinical Trials
Bioavailability Study of Long...

Bioavailability Study of Long Chain Omega-3 Fatty Acids From a Gastric Stable Emulsion

Last Updated: 2010-02-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

27 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-03-31

Study Completion Date

2009-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to compare the short term absorption of EPA and DHA from triglycerides (TG) released from normal soft gel capsules and from the new patent pending vehicle providing a gastric stable emulsion.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Bioavailability of Fish Oils: Emulsified Versus Capsular Triglyceride

NCT01488747

Healthy Adults

COMPLETED NA

Bioavailability of Omega-3 Fatty Acids From Fish Oil Supplements

NCT06665464

Nutrition Absorption, Metabolism and Excretion in Healthy Volunteers Fish Oils +1 more

COMPLETED NA

A Study in Healthy Subjects to Compare the Bioavailability of EPA + DHA

NCT06629103

Optimal Absorption of Omega-3 Healthy

ACTIVE_NOT_RECRUITING PHASE4

Comparative Study of Three Different Formulations of Omega-3 (EPA+DHA)

NCT04159532

Healthy Adults

COMPLETED PHASE4

Comparing the Pharmacological Profile of Formulations Containing Omega 3 Fatty Acids

NCT05394701

Pharmacokinetics

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The present study comprises the design of as well as the effect of pre-emulsification of ω-3 fatty acids on the bioavailability of docosahexaenoic acid and eicosapentaenoic acid. In-vitro studies have shown that long-term steric stabilization of an o/w-emulsion is obtained by arresting the oil droplets in a gelatin continuous gel matrix. The emulsion was also stable upon dissolution of the gel matrix at physiological conditions in-vitro and is hence referred to as a gastric stable emulsion (GSE).

In the bioavailability study, healthy young students were recruited and presented two different single-dose treatments of fish oil containing 5 grams of ω-3 fatty acids; one group receiving the fatty acids in traditional soft gel capsules, whereas the other group received the fatty acids using the GSE technology. Time resolved (2 - 26 hours) blood plasma analysis after intake of this single dose ω-3 fatty acids revealed significantly increased AUC0-26h and Cmax of EPA and EPA + DHA when administered as GSE compared to traditional soft gel capsules.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Healthy

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.