Scoliosis Surgery Using the PASS® LP System

NCT ID: NCT01019109

Last Updated: 2018-03-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

79 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-05-31

Study Completion Date

2016-07-31

Brief Summary

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The purpose of this study is to find out the outcomes of using the PASS LP System to correct idiopathic scoliosis. This system is a unique set of spinal instrumentation used to surgically correct the rotation and deformity of the spine that is caused by scoliosis. Also, this study wants to find out the effects this system has on the physical appearance and quality of life for patients with scoliosis.

Detailed Description

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The aim of this study is to evaluate the clinical, functional and radiographic outcomes following the reduction of idiopathic scoliosis.

The following will be evaluated

1. The 3D correction of scoliosis:

* Reduction of scoliosis in the coronal plane (Cobb angles)
* Correction in the sagittal plane (kyphotic and lordotic angles)
* Correction of the axial vertebral rotation in the transverse plane
2. The functional and aesthetic outcomes

Conditions

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Idiopathic Scoliosis

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Titanium rod

Titanium rods used as a part of PSF construct

Posterior Spinal Fusion Device: Titanium rod arm used titanium rods, and CoCr rod arm used Cobalt Chrome rods as a part of the construct.

Intervention Type DEVICE

PASS LP Implant System is designed to contribute to correction and surgical stabilization of the thoracic, lumbar and sacral spine only. These implants are designed to stabilize the spine during normal development of solid bony consolidation which takes about 18 months. The internal fixation devices are composed of screws, hooks,rods, plates, cross links, connection and locking devices. The range of different sizes and shapes of the implants allows the surgeon to adapt to the pathology and morphology of each of his patients.

CoCr Rod

Cobalt Chrome rods used as a part of PSF construct

Posterior Spinal Fusion Device: Titanium rod arm used titanium rods, and CoCr rod arm used Cobalt Chrome rods as a part of the construct.

Intervention Type DEVICE

PASS LP Implant System is designed to contribute to correction and surgical stabilization of the thoracic, lumbar and sacral spine only. These implants are designed to stabilize the spine during normal development of solid bony consolidation which takes about 18 months. The internal fixation devices are composed of screws, hooks,rods, plates, cross links, connection and locking devices. The range of different sizes and shapes of the implants allows the surgeon to adapt to the pathology and morphology of each of his patients.

Interventions

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Posterior Spinal Fusion Device: Titanium rod arm used titanium rods, and CoCr rod arm used Cobalt Chrome rods as a part of the construct.

PASS LP Implant System is designed to contribute to correction and surgical stabilization of the thoracic, lumbar and sacral spine only. These implants are designed to stabilize the spine during normal development of solid bony consolidation which takes about 18 months. The internal fixation devices are composed of screws, hooks,rods, plates, cross links, connection and locking devices. The range of different sizes and shapes of the implants allows the surgeon to adapt to the pathology and morphology of each of his patients.

Intervention Type DEVICE

Other Intervention Names

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PASS® LP Spinal System Low Profile Polyaxial Spine System Pedicular Screw System

Eligibility Criteria

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Inclusion Criteria

* Idiopathic scoliosis requiring posterior spinal instrumentation and fusion
* Male and female

Exclusion Criteria

* Neuromuscular or degenerative scoliosis
* Spinal cord abnormalities with any neurologic symptoms or signs
* Spinal cord lesions requiring neurosurgical interventions, such as hydromyelia requiring Arnold Chiari decompression
* Primary muscle diseases, such as muscular dystrophy
* Neurologic diseases (e.g. Charcot-Marie Tooth, Guillain-Barre syndrome, cerebral palsy, or spina bifida, Neurofibroma)
* Primary abnormalities of bones (e.g. osteogenesis imperfecta)
* Congenital scoliosis
* Scoliosis requiring anterior release
* Previous spinal surgery
* Patient who is unable to complete a self-administered patient questionnaire
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medicrea, USA Corp.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Dennis Devito, M.D.

Role: PRINCIPAL_INVESTIGATOR

Children's Healthcare of Atlanta, GA

Andrew King, M.D.

Role: PRINCIPAL_INVESTIGATOR

LSU Health Sciences Center-New Orleans, LA

Mark Willits, M.D.

Role: PRINCIPAL_INVESTIGATOR

Nationwide Children's Hospital- Columbus, OH

Afshin Aminian, MD

Role: PRINCIPAL_INVESTIGATOR

Chilren's Hospital of Orange County

Locations

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Children's Healthcare of Atlanta

Atlanta, Georgia, United States

Site Status

LSU Health Sciences Center

New Orleans, Louisiana, United States

Site Status

Nationwide Children's Hospital

Columbus, Ohio, United States

Site Status

Countries

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United States

Other Identifiers

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#0305

Identifier Type: -

Identifier Source: org_study_id

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