Umbilical Cord Serum Eye Drops

NCT ID: NCT01016158

Last Updated: 2009-11-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Study Start Date

2006-04-30

Study Completion Date

2009-10-31

Brief Summary

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In the present study, the investigators investigated the efficacy of umbilical cord serum eye drops for the treatment of patients with recurrent corneal erosions. Group A were treated with 20% umbilical cord serum eye drops 3 to 4 times a day in addition to artificial tears, and group B were treated with artificial tears only. Ophthalmic examinations including visual acuity measurement and slit lamp biomicroscopy were performed before and every month after treatment. Recurrence was defined as the presence of clinical symptoms accompanied by epithelial defects in the cornea.

Detailed Description

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Conditions

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Recurrent Corneal Erosion

Keywords

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Umbilical cord serum Recurrent corneal erosion

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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umbilical cord serum eyedrops

patients with recurrent corneal erosions were treated with 20% umbilical cord serum eye drops 3 to 4 times a day in addition to artificial tears

Group Type EXPERIMENTAL

Umbilical cord serum eyedrops

Intervention Type DRUG

20% umbilical cord serum eye drops 3 to 4 times a day

Interventions

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Umbilical cord serum eyedrops

20% umbilical cord serum eye drops 3 to 4 times a day

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* patients with recurrent corneal erosions

Exclusion Criteria

* none
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Chonnam National University Hospital

OTHER

Sponsor Role lead

Locations

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Chonnam National University Hospital

Gwangju, , South Korea

Site Status

Countries

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South Korea

References

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Yoon KC, Im SK, Park YG, Jung YD, Yang SY, Choi J. Application of umbilical cord serum eyedrops for the treatment of dry eye syndrome. Cornea. 2006 Apr;25(3):268-72. doi: 10.1097/01.ico.0000183484.85636.b6.

Reference Type RESULT
PMID: 16633024 (View on PubMed)

del Castillo JM, de la Casa JM, Sardina RC, Fernandez RM, Feijoo JG, Gomez AC, Rodero MM, Sanchez JG. Treatment of recurrent corneal erosions using autologous serum. Cornea. 2002 Nov;21(8):781-3. doi: 10.1097/00003226-200211000-00010.

Reference Type RESULT
PMID: 12410036 (View on PubMed)

Yoon KC, You IC, Im SK, Jeong TS, Park YG, Choi J. Application of umbilical cord serum eyedrops for the treatment of neurotrophic keratitis. Ophthalmology. 2007 Sep;114(9):1637-42. doi: 10.1016/j.ophtha.2006.12.014. Epub 2007 Mar 26.

Reference Type RESULT
PMID: 17382396 (View on PubMed)

Other Identifiers

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I-2009-11-135

Identifier Type: -

Identifier Source: org_study_id