Effectiveness of Oral Antibiotics in the Treatment of Severe Acute Malnutrition
NCT ID: NCT01000298
Last Updated: 2011-07-06
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
2700 participants
INTERVENTIONAL
2009-12-31
2011-05-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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Placebo
Placebo
liquid placebo medication given twice per day for 7 days
Amoxicillin
Amoxicillin
liquid amoxicillin given twice per day for 7 days
cefdinir
cefdinir
Cefdinir
liquid cefdinir given twice per day for 7 days
Interventions
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Placebo
liquid placebo medication given twice per day for 7 days
Amoxicillin
liquid amoxicillin given twice per day for 7 days
Cefdinir
liquid cefdinir given twice per day for 7 days
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Kwashiorkor or Marasmus
* Qualifies for home-based therapeutic feeding with RUTF
Exclusion Criteria
* Unable to consume test-dose of RUTF in clinic
* Parent refusal to participate and return for follow-up
6 Months
5 Years
ALL
No
Sponsors
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Washington University School of Medicine
OTHER
Responsible Party
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Washington Univeristy in St. Louis
Principal Investigators
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Mark J. Manary, MD
Role: PRINCIPAL_INVESTIGATOR
Washington University School of Medicine
Locations
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St. Louis Nutrition Project
Blantyre, , Malawi
Countries
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References
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Trehan I, Goldbach HS, LaGrone LN, Meuli GJ, Wang RJ, Maleta KM, Manary MJ. Antibiotics as part of the management of severe acute malnutrition. Malawi Med J. 2016 Sep;28(3):123-130.
Trehan I, Goldbach HS, LaGrone LN, Meuli GJ, Wang RJ, Maleta KM, Manary MJ. Antibiotics as part of the management of severe acute malnutrition. N Engl J Med. 2013 Jan 31;368(5):425-35. doi: 10.1056/NEJMoa1202851.
Other Identifiers
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MJM-antibiotics
Identifier Type: -
Identifier Source: org_study_id
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