Collecting Tissue Samples From Patients With Cancer Undergoing Radiation Therapy and Healthy Participants
NCT ID: NCT00992303
Last Updated: 2025-05-14
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
10000 participants
OBSERVATIONAL
2009-09-30
2029-12-31
Brief Summary
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PURPOSE: This research study is collecting tissue samples from patients with cancer undergoing radiation therapy. Healthy participants will also be allowed on the trial so their samples can be used in comparison to patients with malignancy
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Detailed Description
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Primary
* To maintain and create a University of Texas Southwestern Medical Center (UTSW) Radiation Oncology Tissue Resource and Registry/Database that will be used to explore genetic variations contributing to clinical outcomes through tissue analysis and outcome correlation. Tissue will be stored by the UTSTR and the database managed by Radiation Oncology.
Secondary
* To document disease outcome (local recurrence, distant metastasis, overall survival) by treatment regimen and disease site.
* To document toxicity by treatment regimen and disease site.
* To establish a prospective registry/database consisting of patient demographics and outcomes to be used for future research.
OUTLINE: Tissue, including surgical waste, venous blood/serum, urine, bone marrow, and other body fluids, may be collected (at planned surgery and routine medical visits) and preserved for future research. Demographic and disease and treatment information is obtained from patients (by interview or questionnaire), from medical records, and from national datasets. Patients may also be asked to provide additional blood samples and/or a small skin-punch biopsy sample.
Patients are followed up every 6 months for the first two years following treatment and then yearly thereafter.
Conditions
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Study Design
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CASE_ONLY
CROSS_SECTIONAL
Interventions
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biologic sample preservation procedure
medical chart review
questionnaire administration
Eligibility Criteria
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Inclusion Criteria
Criteria for ineligibility:
-Patients not available for follow-up/future contact
18 Years
ALL
Yes
Sponsors
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University of Texas Southwestern Medical Center
OTHER
Responsible Party
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Robert Timmerman
Professor
Principal Investigators
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Robert Timmerman, MD
Role: PRINCIPAL_INVESTIGATOR
University of Texas Southwestern Medical Center - Dallas
Locations
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UT Southwestern Medical Center
Dallas, Texas, United States
Countries
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Central Contacts
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Facility Contacts
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Sarah Neufeld
Role: primary
Other Identifiers
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SCCC-032009-049
Identifier Type: -
Identifier Source: secondary_id
CDR0000653406
Identifier Type: -
Identifier Source: secondary_id
STU 072010-098
Identifier Type: -
Identifier Source: org_study_id
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