Creatine Supplementation and Diabetes

NCT ID: NCT00992043

Last Updated: 2010-03-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

28 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-10-31

Study Completion Date

2010-01-31

Brief Summary

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Creatine supplementation is capable of improving glucose tolerance in healthy subjects. The researchers aim to investigate whether this supplement can affect metabolic control in diabetic patients.

Detailed Description

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Conditions

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Diabetes Renal Function

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

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exercise and placebo

Group Type PLACEBO_COMPARATOR

creatine

Intervention Type DIETARY_SUPPLEMENT

Exercise training

Intervention Type OTHER

exercise and creatine

Group Type EXPERIMENTAL

creatine

Intervention Type DIETARY_SUPPLEMENT

Exercise training

Intervention Type OTHER

Interventions

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creatine

Intervention Type DIETARY_SUPPLEMENT

Exercise training

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* males and females type 2 diabetic patients
* glycated hemoglobin between \> 9%
* non insulin users
* physically inactive
* only metformin and/or sulfonylurea users
* BMI \> 30 kg/m2
* age of years \> 50 y
Minimum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Sao Paulo

OTHER

Sponsor Role lead

Responsible Party

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University of Sao Paulo

Principal Investigators

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Bruno Gualano, PhD ongoing

Role: PRINCIPAL_INVESTIGATOR

University of Sao Paulo

Locations

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General Hospital - School of Medicine - University of Sao Paulo

São Paulo, São Paulo, Brazil

Site Status

Countries

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Brazil

References

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Gualano B, Lugaresi R, de Salles Painelli V, Queiroz AC, Artioli G, Roschel H, Otaduy MC, Leite Cda C, Lancha AH Jr. Creatine supplementation does not augment muscle carnosine content in type 2 diabetic patients. Appl Physiol Nutr Metab. 2011 Oct;36(5):764-7. doi: 10.1139/h11-083.

Reference Type DERIVED
PMID: 21999299 (View on PubMed)

Gualano B, de Salles Painelli V, Roschel H, Lugaresi R, Dorea E, Artioli GG, Lima FR, da Silva ME, Cunha MR, Seguro AC, Shimizu MH, Otaduy MC, Sapienza MT, da Costa Leite C, Bonfa E, Lancha Junior AH. Creatine supplementation does not impair kidney function in type 2 diabetic patients: a randomized, double-blind, placebo-controlled, clinical trial. Eur J Appl Physiol. 2011 May;111(5):749-56. doi: 10.1007/s00421-010-1676-3. Epub 2010 Oct 26.

Reference Type DERIVED
PMID: 20976468 (View on PubMed)

Other Identifiers

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eefeusp2

Identifier Type: -

Identifier Source: org_study_id

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