A New Adaptive Feeding Plan for Newborns

NCT ID: NCT00984230

Last Updated: 2013-06-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

186 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-09-30

Study Completion Date

2011-02-28

Brief Summary

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The purpose of this clinical trial is to identify the infant formula(s) for which the investigators get the closest gut maturation index compared to the one they get with breastfed babies.

Detailed Description

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Conditions

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Infant Nutrition

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Breastfeeding (Reference)

Group Type NO_INTERVENTION

No interventions assigned to this group

Basic starter formula: BSF

Group Type ACTIVE_COMPARATOR

BSF

Intervention Type OTHER

feeding amount according to individual baby need

BSF + Lactoferrin + Probiotics + OS

Group Type EXPERIMENTAL

BSF + Lactoferrin + Probiotics + OS

Intervention Type OTHER

feeding amount according to individual baby need

BSF + Lactoferrin + Probiotics

Group Type EXPERIMENTAL

BSF + Lactoferrin + Probiotics

Intervention Type OTHER

feeding amount according to individual baby need

Interventions

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BSF

feeding amount according to individual baby need

Intervention Type OTHER

BSF + Lactoferrin + Probiotics

feeding amount according to individual baby need

Intervention Type OTHER

BSF + Lactoferrin + Probiotics + OS

feeding amount according to individual baby need

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Healthy newborn infant
* Full term infant (≥ 37 weeks gestation; \< 42 weeks gestation)
* Birth weight from 2500g to 4500g
* For the formula-fed groups: babies whose mothers elected not to breastfeed at all
* For the breastfed group: babies whose mothers elected to exclusively breastfeed for at least 2 months
* Newborn whose parents / caregivers can be expected to comply with the protocol
* Study explained and written information given
* Informed consent signed

Exclusion Criteria

* Mother who had antibiotics in the 7 days preceding delivery
* Caesarian section
* Multiple birth
* Congenital illness or malformation that may affect normal growth
* Significant pre-natal and/or post-natal disease
* Newborn participating in another clinical trial
Minimum Eligible Age

1 Day

Maximum Eligible Age

3 Days

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Société des Produits Nestlé (SPN)

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jean-Charles Pr Picaud

Role: PRINCIPAL_INVESTIGATOR

Service de Réanimation Néonatale et Néonatologie, Hôpital de la Croix Rousse

Locations

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Department of Pediatrics

Vienna, , Austria

Site Status

Service de Réanimation Néonatale et Néonatologie, Hôpital de la Croix Rousse

Lyon, , France

Site Status

Maternité Régionale, Service de Néonatologie

Nancy, , France

Site Status

Service de Néonatologie

Nantes, , France

Site Status

Hôpital Charles Nicolle, Département de Pédiatrie

Rouen, , France

Site Status

Alexandra Regional General Hospital, Department of Neonatology

Palaió Fáliro, Athens, Greece

Site Status

Countries

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Austria France Greece

Other Identifiers

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07.22.INF

Identifier Type: -

Identifier Source: org_study_id

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